Table 2 Antibiotic duration and clinical outcomes
From: Reducing the use of empiric antibiotic therapy in COVID-19 on hospital admission
Pre-Intervention (N = 76) | Post-Intervention (N = 170) | p-value | |
|---|---|---|---|
All antibiotics duration, median days (IQR) | 2.3 (1, 3.9) | 1 (0.5, 2.1) | < 0.001 |
Atypical coverage duration, median days (IQR) | 3.8 (3, 4.1) | 1 (0.4, 1.6) | < 0.001 |
Clostridioides difficile infection | 1 (1) | 2 (1) | > 0.99 |
Antibiotics re-initiated | |||
Any-indication | 6 (8) | 24 (14) | 0.2 |
Bacterial pneumoniaa | 2 (2.6) | 16 (9) | 0.07 |
Readmission within 30 days | |||
All-cause | 5 (7) | 23 (13.5) | 0.2 |
Bacterial pneumonia | 1 (1.3) | 3 (1.8) | > 0.99 |
Mortality (all-cause) | 13 (17) | 21 (12) | 0.42 |
Length of stay, median (IQR) | 7 (4, 13.2) | 7 (4, 12) | 0.5 |