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Table 3 Quality assessment rating of systematic reviews included in the COVID-19 overview

From: Coronavirus disease (COVID-19) pandemic: an overview of systematic reviews

Study identification AMSTAR 2 assessment for individual items AMSTAR 2 Score Summary Funding or support for the systematic review
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Final Rating  
Adhikari et al Y PY Y PY Y N N Y N N NA NA N Y NA Y Critically Low Y
Borges do Nascimento et al Y Y Y PY Y Y N Y Y N Y Y Y Y N Y Critically Low No
Cortegiani et al Y PY Y Y Y Y N Y N N NA NA N N NA Y Critically Low No
Li B et al. (Prevalence…) Y N Y N N N N PY Y N Y N N Y Y Y Critically Low Y
Li LQ et al. (2019 novel…) Y N Y PY Y Y N PY Y N Y Y Y Y Y Y Critically Low Y
Lippi & Henry (Active smoking…) Y N N PY N N N N N N N N N N N Y Critically Low Not reported
Lippi et al. (Cardiac troponin…) Y N N PY N N N N N N N N N N N Y Critically Low Not reported
Lippi & Plebani (Procalcitonin…) Y N N PY N N N N N N N N N Y N N Critically Low Not reported
Lippi et al. (Thrombocyto…) Y N N PY Y N N N N N N N N Y N Y Critically Low Not reported
Ludvigsson Y N N PY N N N N N N NA NA N N NA Y Critically Low No
Lupia et al Y N N N N N N N N N NA NA N N NA Y Critically Low No
Marasinghe Y N Y N N NA N NA NA NA NA NA NA NA NA Y Critically Low No
Mullins et al Y N N N N N Y N N N NA NA N N NA Y Critically Low No
Pang et al N N Y N Y N N Y N N NA NA N N NA Y Critically Low Y
Rodriguez-Morales et al Y Y Y PY Y Y N PY N N Y N N N Y Y Critically Low Y
Salehi et al Y N N N Y Y N N Y N NA NA Y N NA N Critically Low Not reported
Sun et al Y N Y PY N N N N Y N Y N Y Y Y Y critically Low Not reported
Yang et al Y N Y PY N Y N N N N Y N N Y N Y Critically Low Not reported
  1. Note - Yes; N No; PY Partially yes; NA Not applicable
  2. AMSTAR 2 Questions:
  3. 1. “Did the research questions and inclusion criteria for the review include the components of PICO?”
  4. 2. “Did the report of the review contain an explicit statement that the review methods were established prior to the conduct of the review and did the report justify any significant deviations from the protocol?”;
  5. 3. “Did the review authors explain their selection of the study designs for inclusion in the review?”;
  6. 4. “Did the review authors use a comprehensive literature search strategy?”
  7. 5. “Did the review authors perform study selection in duplicate?”;
  8. 6. “Did the review authors perform data extraction in duplicate?”;
  9. 7. “Did the review authors provide a list of excluded studies and justify the exclusions?”
  10. 8. “Did the review authors describe the included studies in adequate detail?”;
  11. 9. “Did the review authors use a satisfactory technique for assessing the risk of bias (RoB) in individual studies that were included in the review?”;
  12. 10. “Did the review authors report on the sources of funding for the studies included in the review?
  13. 11. “If meta-analysis was performed did the review authors use appropriate methods for statistical combination of results?”
  14. 12. “If meta-analysis was performed, did the review authors assess the potential impact of RoB in individual studies on the results of the meta-analysis or other evidence synthesis?”;
  15. 13. “Did the review authors account for RoB in individual studies when interpreting/ discussing the results of the review?”;
  16. 14. “Did the review authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the review?”;
  17. 15. “If they performed quantitative synthesis did the review authors carry out an adequate investigation of publication bias (small study bias) and discuss its likely impact on the results of the review?”;
  18. 16. “Did the review authors report any potential sources of conflict of interest, including any funding they received for conducting the review?”
  19. *BOLD means critical domains
  20. High confidence → No critical or maximum one non-critical weakness // Moderate confidence→ No critical with > 1 non-critical weaknesses
  21. Low confidence→ One critical +/− non-critical weaknesses // Critically low confidence→ > 1 critical +/− non-critical weaknesses