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Table 1 Descriptive summary of the 18 systematic reviews included in the analysis (Adhikari is a scoping review; Mullins et al. is a rapid review)

From: Coronavirus disease (COVID-19) pandemic: an overview of systematic reviews

Review identification

Journal and IF

Time frame assessed

Databases

Number of included studies

Study design of included studies

Methodological quality assessment

Meta-analysis performed

Patients: total (n)

Mean/Median age of included patients (years)

Male sex (%)

Adhikari et al

Infectious Diseases of Poverty, 3.12

January 1, 2020 to January 31, 2020

bioRxiv, medRxiv, chemRxiv, Google Scholar, PubMed, CNKI and WanFang Data; grey literature (online material released by the National Health Commission of the People’s Republic of China, Chinese Center for Disease Prevention and Control, and the WHO)

65

Cross-sectional, molecular, diagnostic, theoretical and mathematical modeling studies and reviews

N

N

Not reported

Median: 59, ranging from 2 to 89 years, when reported

Most cases were males; 59–68% where reported

Borges do Nascimento et al

Journal of Clinical Medicine, 5.688

January 1, 2019 to February 24, 2020

MEDLINE, Embase, CENTRAL (Cochrane Library), Scopus and LILACS

60

Case reports, case series and observational studies/epidemiological reports

Y

Y

59,254

Not reported; ranging from 3 months to 99 years

51.92

Cortegiani et al

Journal of Critical Care, 2.783

Inception up to March 1, 2020

PubMed and Embase, Chinese Clinical Trial Registry, ClinicalTrials.gov, and ICTPR (WHO)

29

Narrative letters, in-vitro study, editorial, expert consensus paper, national guideline documents and clinical trialsa

N

N

3090

Not reported

Not reported

Li B et al. (Prevalence…)

Clinical Research in Cardiology, 4.907

December 2019 to February 2020

PubMed, medRxiv and Embase

6

Case series and observational studies

N

Y

1,527

Median: 49.75

57.80; ranging from 44.5 to 77

Li LQ et al. (2019 novel…)

Journal of Medical Virology, 2.049

December 2019 to February 2020

PubMed, Embase, Web of Science, WanFang Data, and CNKI

10.

Case reports, case series and observational studies

Y

Y

1994

Median: 49.94 (without one study)

63.35; ranging from 44.5 to 77

Lippi & Henry (Active smoking…)

European Journal of Internal Medicine, 3.660

2019 to March 9, 2020

MEDLINE (via PubMed interface), Scopus and Web of Science

5

Case series and observational studies

N

Y

1399

Not reported

More cases

Lippi et al. (Cardiac troponin…)

Progress in Cardiovascular Diseases, 6.162

2019 to March 4, 2020

MEDLINE (via PubMed interface), Scopus and Web of Science

4

Observational studies

N

Y

341

Not reported

Not rported

Lippi & Plebani (Procalcitonin…)

Clinica Chimica Acta, 2.735

Inception to March 3, 2020

MEDLINE (PubMed interface), Scopus and Web of Science

4

Observational studies

N

Y

Not reported

Not reported

Not reported

Lippi et al. (Thrombocyto…)

Clinica Chimica Acta, 2.735

2019 to March 6, 2020

Medline (PubMed interface), Scopus and Web of Science

9

Observational studies

N

Y

1,799

Not reported

71.71

Ludvigsson

Acta Pediatrica, 2.265

January 1, 2020 to March 18, 2020

MEDLINE (via PubMed interface), Embase and ICTPR

45

Case reports, case series and observational studies

N

N

Not summarized

6.7 (where reported) and newborn infants

56.6 (where reported)

Lupia et al

Journal of Global Antimicrobial Resistance, 2469

November 30, 2019 to February 13, 2020

PubMed and Cochrane Library

13

Case reports, case series and observational studies

N

N

874

42.25 (without one study ranging from 19 to 63)

53.67

Marasinghe

Systematic Review, 1.692

Inception up to February 2020

Cochrane Library, PubMed, Embase, Google Scholar and Scopus

0

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

Not applicable

Mullins et al

Ultrasound in Obstetrics & Gynecology, 5.595

Inception up to March 10, 2020

PubMed and MedRxiv

21

Case reports or case series

N

N

62 (32 mothers and 30 newborns)

Median: 30

Not applicable

Pang et al

Journal of Clinical Medicine, 5.688

December 1, 2019 to February 6, 2020

PubMed, Embase and Cochrane Library

27

Randomized controlled trials (RCTs) and validation trials

N

N

656 for SARS-COV-2

Not reported

Not reported

Rodriguez-Morales et al

Travel Medicine and Infectious Disease, 4.868

January 1, 2020 to February 23, 2020

MEDLINE (via PubMed interface), Scopus and Web of Science

58

Case reports, case series and cross-sectional studies

Y

Y (19 studies)

2874 (19 studies)

Mean: 51.97

55.9

Salehi et al

American Journal of Roentgenology, 3.161

Inception up to February 12, 2020 (updated on February 19, 2020)

PubMed, EMBASE, Google Scholar, and the World Health Organization Database

30

Case reports and case series

Y

N

919

Not reported

Not reported

Sun et al

Journal of Medical Virology, 2.049

Inception up to February 24, 2020

PubMed, Embase and Cochrane Library and additional databases/sources (including the China CDC)

10

Case reports, case series and observational studies

Y

Y

50,466

Mean: 44.25

52.01

Yang et al

International Journal of Infectious Diseases, 3.538

January 1, 2020 to February 25, 2020

PubMed, Embase and Web of Science

7

Case series and observational studies

N

Y

1576

Median: 46.0

51.6

  1. a Five studies did not fit the classification for study design: one narrative letter, one editorial, one expert consensus paper and two national guideline documents