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Table 1 Descriptive summary of the 18 systematic reviews included in the analysis (Adhikari is a scoping review; Mullins et al. is a rapid review)

From: Coronavirus disease (COVID-19) pandemic: an overview of systematic reviews

Review identification Journal and IF Time frame assessed Databases Number of included studies Study design of included studies Methodological quality assessment Meta-analysis performed Patients: total (n) Mean/Median age of included patients (years) Male sex (%)
Adhikari et al Infectious Diseases of Poverty, 3.12 January 1, 2020 to January 31, 2020 bioRxiv, medRxiv, chemRxiv, Google Scholar, PubMed, CNKI and WanFang Data; grey literature (online material released by the National Health Commission of the People’s Republic of China, Chinese Center for Disease Prevention and Control, and the WHO) 65 Cross-sectional, molecular, diagnostic, theoretical and mathematical modeling studies and reviews N N Not reported Median: 59, ranging from 2 to 89 years, when reported Most cases were males; 59–68% where reported
Borges do Nascimento et al Journal of Clinical Medicine, 5.688 January 1, 2019 to February 24, 2020 MEDLINE, Embase, CENTRAL (Cochrane Library), Scopus and LILACS 60 Case reports, case series and observational studies/epidemiological reports Y Y 59,254 Not reported; ranging from 3 months to 99 years 51.92
Cortegiani et al Journal of Critical Care, 2.783 Inception up to March 1, 2020 PubMed and Embase, Chinese Clinical Trial Registry, ClinicalTrials.gov, and ICTPR (WHO) 29 Narrative letters, in-vitro study, editorial, expert consensus paper, national guideline documents and clinical trialsa N N 3090 Not reported Not reported
Li B et al. (Prevalence…) Clinical Research in Cardiology, 4.907 December 2019 to February 2020 PubMed, medRxiv and Embase 6 Case series and observational studies N Y 1,527 Median: 49.75 57.80; ranging from 44.5 to 77
Li LQ et al. (2019 novel…) Journal of Medical Virology, 2.049 December 2019 to February 2020 PubMed, Embase, Web of Science, WanFang Data, and CNKI 10. Case reports, case series and observational studies Y Y 1994 Median: 49.94 (without one study) 63.35; ranging from 44.5 to 77
Lippi & Henry (Active smoking…) European Journal of Internal Medicine, 3.660 2019 to March 9, 2020 MEDLINE (via PubMed interface), Scopus and Web of Science 5 Case series and observational studies N Y 1399 Not reported More cases
Lippi et al. (Cardiac troponin…) Progress in Cardiovascular Diseases, 6.162 2019 to March 4, 2020 MEDLINE (via PubMed interface), Scopus and Web of Science 4 Observational studies N Y 341 Not reported Not rported
Lippi & Plebani (Procalcitonin…) Clinica Chimica Acta, 2.735 Inception to March 3, 2020 MEDLINE (PubMed interface), Scopus and Web of Science 4 Observational studies N Y Not reported Not reported Not reported
Lippi et al. (Thrombocyto…) Clinica Chimica Acta, 2.735 2019 to March 6, 2020 Medline (PubMed interface), Scopus and Web of Science 9 Observational studies N Y 1,799 Not reported 71.71
Ludvigsson Acta Pediatrica, 2.265 January 1, 2020 to March 18, 2020 MEDLINE (via PubMed interface), Embase and ICTPR 45 Case reports, case series and observational studies N N Not summarized 6.7 (where reported) and newborn infants 56.6 (where reported)
Lupia et al Journal of Global Antimicrobial Resistance, 2469 November 30, 2019 to February 13, 2020 PubMed and Cochrane Library 13 Case reports, case series and observational studies N N 874 42.25 (without one study ranging from 19 to 63) 53.67
Marasinghe Systematic Review, 1.692 Inception up to February 2020 Cochrane Library, PubMed, Embase, Google Scholar and Scopus 0 Not applicable Not applicable Not applicable Not applicable Not applicable Not applicable
Mullins et al Ultrasound in Obstetrics & Gynecology, 5.595 Inception up to March 10, 2020 PubMed and MedRxiv 21 Case reports or case series N N 62 (32 mothers and 30 newborns) Median: 30 Not applicable
Pang et al Journal of Clinical Medicine, 5.688 December 1, 2019 to February 6, 2020 PubMed, Embase and Cochrane Library 27 Randomized controlled trials (RCTs) and validation trials N N 656 for SARS-COV-2 Not reported Not reported
Rodriguez-Morales et al Travel Medicine and Infectious Disease, 4.868 January 1, 2020 to February 23, 2020 MEDLINE (via PubMed interface), Scopus and Web of Science 58 Case reports, case series and cross-sectional studies Y Y (19 studies) 2874 (19 studies) Mean: 51.97 55.9
Salehi et al American Journal of Roentgenology, 3.161 Inception up to February 12, 2020 (updated on February 19, 2020) PubMed, EMBASE, Google Scholar, and the World Health Organization Database 30 Case reports and case series Y N 919 Not reported Not reported
Sun et al Journal of Medical Virology, 2.049 Inception up to February 24, 2020 PubMed, Embase and Cochrane Library and additional databases/sources (including the China CDC) 10 Case reports, case series and observational studies Y Y 50,466 Mean: 44.25 52.01
Yang et al International Journal of Infectious Diseases, 3.538 January 1, 2020 to February 25, 2020 PubMed, Embase and Web of Science 7 Case series and observational studies N Y 1576 Median: 46.0 51.6
  1. a Five studies did not fit the classification for study design: one narrative letter, one editorial, one expert consensus paper and two national guideline documents