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Table 2 Cox regression model of variables related to seroconversion (person/days)

From: Longitudinal assessment of SARS-CoV-2 IgG seroconversionamong front-line healthcare workers during the first wave of the Covid-19 pandemic at a tertiary-care hospital in Chile

Variables

Univariate

Multivariate

HR (95%CI)

p value

HR (95%CI)

p value

Gender; Female

1.45 (0.80–2.63)

0.22

  

Older Age

0.97 (0.95–0.99)

0.04

0.97 (0.94–0.99)

0.03

Work area

High-risk for Covid-19

Low-risk for Covid-19

2.45 (0.59–10.03)

0.21

  

Comorbidities & medications

Diabetes

7.04 (1.68–29.61)

0.008

17.42 (3.9–77.83)

0.00

Hypertension

0.44 (0.11–1.82)

0.26

  

Obesity

0.61 (0.19–1.96)

0.42

  

Asthma

0.98 (0.24–4.00)

0.98

  

Smoker

0.38 (0.17–0.89)

0.025

0.38 (0.16–0.93)

0.03

No comorbidities

0.78 (0.48–1.28)

0.33

  

Use of ACE inhibitors

0.67 (0.21–2.14)

0.50

  

Profession

Physician

0.89 (0.54–1.48)

0.66

  

Respiratory therapist

0.91 (0.33–2.51)

0.86

  

Nurse

1.35 (0.81–2.25)

0.26

  

Technician/paramedic

0.87 (0.47–1.60)

0.65

  

Administrative worker

0.05 (0.0–6078.3)

0.61

  

Clinical Unit

Intensive care unit

0.78 (0.41–1.49)

0.46

  

Stepdown unit

1.37 (0.79–2.37)

0.26

  

Medical ward

1.50 (0.88–2.55)

0.13

  

Emergency department

0.60 (0.33–1.11)

0.10

  

Epidemiological risk factors

Non-occupational Covid-19 contact

1.41 (0.57–3.52)

0.46

  

International travel (previous 3 months)

1.82 (1.11–2.99)

0.018

1.59 (0.95–2.68)

0.08

Covid-19 related symptoms within 4 weeks of serology testing

No symptoms

0.88 (0.53–1.45)

0.61

  

Fever

3.43 (1.07–11.02)

0.04

7.54 (2.24–25.34)

0.001

Cough

1.47 (0.75–2.88)

0.27

  

Myalgia

0.96 (0.30–3.07)

0.96

  

Anosmia or Ageusia

7.35 (4.47–12.07)

0.00

6.7 (3.89–11.52)

0.00

Chest pain

2.47 (1.06–5.74)

0.04

1.22 (0.49–3.05)

0.66