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Table 2 Cox regression model of variables related to seroconversion (person/days)

From: Longitudinal assessment of SARS-CoV-2 IgG seroconversionamong front-line healthcare workers during the first wave of the Covid-19 pandemic at a tertiary-care hospital in Chile

Variables Univariate Multivariate
HR (95%CI) p value HR (95%CI) p value
Gender; Female 1.45 (0.80–2.63) 0.22   
Older Age 0.97 (0.95–0.99) 0.04 0.97 (0.94–0.99) 0.03
Work area
High-risk for Covid-19
Low-risk for Covid-19
2.45 (0.59–10.03) 0.21   
Comorbidities & medications
Diabetes 7.04 (1.68–29.61) 0.008 17.42 (3.9–77.83) 0.00
Hypertension 0.44 (0.11–1.82) 0.26   
Obesity 0.61 (0.19–1.96) 0.42   
Asthma 0.98 (0.24–4.00) 0.98   
Smoker 0.38 (0.17–0.89) 0.025 0.38 (0.16–0.93) 0.03
No comorbidities 0.78 (0.48–1.28) 0.33   
Use of ACE inhibitors 0.67 (0.21–2.14) 0.50   
Profession
Physician 0.89 (0.54–1.48) 0.66   
Respiratory therapist 0.91 (0.33–2.51) 0.86   
Nurse 1.35 (0.81–2.25) 0.26   
Technician/paramedic 0.87 (0.47–1.60) 0.65   
Administrative worker 0.05 (0.0–6078.3) 0.61   
Clinical Unit
Intensive care unit 0.78 (0.41–1.49) 0.46   
Stepdown unit 1.37 (0.79–2.37) 0.26   
Medical ward 1.50 (0.88–2.55) 0.13   
Emergency department 0.60 (0.33–1.11) 0.10   
Epidemiological risk factors
Non-occupational Covid-19 contact 1.41 (0.57–3.52) 0.46   
International travel (previous 3 months) 1.82 (1.11–2.99) 0.018 1.59 (0.95–2.68) 0.08
Covid-19 related symptoms within 4 weeks of serology testing
No symptoms 0.88 (0.53–1.45) 0.61   
Fever 3.43 (1.07–11.02) 0.04 7.54 (2.24–25.34) 0.001
Cough 1.47 (0.75–2.88) 0.27   
Myalgia 0.96 (0.30–3.07) 0.96   
Anosmia or Ageusia 7.35 (4.47–12.07) 0.00 6.7 (3.89–11.52) 0.00
Chest pain 2.47 (1.06–5.74) 0.04 1.22 (0.49–3.05) 0.66