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Table 2 Immunological discordant responses and associated factors among HAART users in Mekelle Hospital and Ayder Comprehensive Specialized Hospital (n = 260)

From: Immunological and virological discordance among people living with HIV on highly active antiretroviral therapy in Tigray, Northern Ethiopia

Characteristics

Immunological discordance

P-value*

Yes n (%)

 

Gender

 Male

3 (2.8)

1.000

 Female

4 (2.6)

Age (years) at HAART initiation

 < 35

2 (2.4)

1.000

 > 35

5 (2.8)

Age (years) at 36 months median time of HAART follow up

 < 39

3 (2.1)

0.706

 > 39

4 (3.4)

Residence

 Rural

1 (2.0)

1.000

 Urban

6 (2.8)

Chronic non-communicable diseasesa

 Yes

0 (0)

1.000

 No

72.8)

TB co-infection

 Yes

4 (9.3)

0.016

 No

3 (1.4)

History of Opportunistic Infections (other than TB)b

 Yes

3 (2.1)

0.704

 No

4 (3.4)

HBV co-infection

 Yes

2 (18.2)

0.05

 No

3 (2.8)

HCV co-infection

 Yes

1 (50.0)

0.062

 No

1 (1.6)

Adherence to treatment

 Poor/fair

2 (11.1)

0.08

 Good

5 (2.1)

WHO clinical stage at baseline

 I and II

0 (0.0)

 

 III and IV

7 (5.1)

 

CD4+ count (cell/μl) at baseline

 < 100

5 (6.5)

0.026

 > 100

2 (1.1)

Regimen given

 TDF basedc

7 (3.6)

 

 AZT basedd

0 (0)

 
  1. Note: *P-value is determined by Fisher’s exact test, INH Isoniazid, TB Tuberculosis, WHO World Health Organization, HBV Hepatitis B virus, HCV Hepatitis C virus. a Includes Hypertension and Diabetic mellitus. b Includes: oral/esophageal candidiasis; Pneumonias; Diarrhea; Zoster e.t.c. c Drugs used concomitantly with TDF (Tenofovir) were: 3TC (lamivudine) + EFV (efaverinz) / NVP (Nevirapine). d Drugs used concomitantly with AZT (zidovudin); were: AZT+ 3TC+ NVP/ EFV