Shedding of infectious SARS-CoV-2 by hospitalized COVID-19 patients in relation to serum antibody responses

BMC Infectious Diseases

Table 2 Detection of SARS-CoV-2 and specific antibody levels in all COVID-19 patients (n = 36)

ID	SARS-CoV-2 PCR (Ct value)			SARS-CoV-2 culture		Anti-SARS-CoV-2 IgG titers	Neutralizing antibody titers	Days after onset of symptom
ID	NPH	Sputum	serum	NPH	Sputum	Anti-SARS-CoV-2 IgG titers	Neutralizing antibody titers	Days after onset of symptom
1	19	21	neg	pos	pos	< 20	< 10	16
2	24	28	neg	pos	neg	< 20	< 10	9
3^a	25	19	neg	pos	neg	40	< 10	9
4^a	26	20	neg	pos	neg	40	10	11
5	32	24	neg	neg	neg	40	10	9
6	neg	23	neg	neg	neg	40	10	10
7^d	33	n/a	neg	neg	n/a	320	10	9
8^b	28	37	38	neg	neg	160	15	10
9	neg	n/a	neg	neg	n/a	320	30	11
10	neg	neg	neg	neg	neg	640	30	12
11	neg	n/a	neg	neg	n/a	40	40	10
12^a	33	n/a	neg	neg	n/a	1280	40	11
13	34	32	neg	neg	neg^f	1280	40	20
14^a	28	n/a	neg	neg	neg	640	60	14
15	neg	31	neg	neg	neg	640	60	18
16	35	neg	neg	neg	neg	1280	60	15
17	35	neg	36	neg	neg	1280	60	48
18^a	30	29	neg	neg	neg	2560	60	28
19^a	neg	neg	neg	neg	neg^e	2560	60	30
20	neg	36	neg	neg	neg	640	80	53
21	neg	34	neg	neg	neg	1280	80	43
22^c	neg	neg	38	neg	neg	2560	80	18
23^a,d	26	20	neg	neg	neg	320	120	9
24	neg	36	neg	neg	neg	2560	120	39
25	neg	neg	neg	neg	neg	2560	120	18
26^a	neg	neg	neg	neg	neg	2560	120	21
27^a	neg	neg	neg	neg	neg	1280	160	21
28	neg	27	neg	neg	neg	1280	160	43
29^a	neg	neg	neg	neg	n/a	1280	240	21
30	neg	28	neg	neg	neg	1280	240	14
31	neg	28	neg	neg	neg^e	1280	240	27
32	neg	neg	neg	neg	neg	2560	240	20
33	neg	neg	neg	neg	neg	2560	240	37
34^a,b	neg	n/a	neg	neg	n/a	1280	320	22
35	neg	32	neg	neg	neg	2560	320	19
36^a	neg	neg	neg	neg	neg	1280	560	26

Abbreviation: neg negative, NPH nasopharynx, pos positive
^atreatment with corticosteroids, ^btreatment with tociluzimab, ^ctreatment with anakinra, ^dremdesivir treatment
^ePositive for herpes simplex 1 in PCR
^fPostive CPE in culture, negative for SARS-CoV-2, herpes simples 1 and 2, cytomegalovirus, adenovirus, bocavirus, enterovirus, metapneumovirus, parainfluenzavirus and rhinovirus

ISSN: 1471-2334