Characteristics | Total cohort (N = 202) | Exposed (prone) group (N = 101) | Unexposed (supine) group (N = 101) | Pair differences or discordances | p* |
---|---|---|---|---|---|
Centre 1 (VS 2) | 90 (45) | 45 (45) | 45 (45) | 0 / 0 | 1 |
Gender (M) | 147 (73) | 74 (73) | 74 (73) | 0 / 0 | 1 |
Age (y) | 61 (48–68) | 61 (46–68) | 61 (52–70) | 1 (−4–8) | 0.63 |
BMI (kg/m2) | 28 (25–34) | 30 (26–35) | 27 (24–31) | -1 (−8.5–3) | 0.003 |
SAPS II score | 54 (43–66) | 54 (43–66) | 53 (44–66) | 0 (−5–6) | 0.94 |
SOFA score | 9 (8–12) | 10 (8–12) | 9 (8–11) | 0 (−3–2) | 0.43 |
Immunosuppressiona | 98 (49) | 51 (51) | 47 (47) | 26 / 22 | 0.67 |
Surgical admission (vs. medical) | 36 (18) | 14 (14) | 22 (22) | 8 / 16 | 0.20 |
Nosocomial patient origin (vs. community) | 98 (49) | 49 (49) | 49 (49) | 25 / 25 | 1 |
Catheterization duration (days) | 17 (8–26) | 19 (9–27) | 14 (8–25) | -1 (−13–6) | 0.049 |
Number of catheter per patient | 2 (1–3) | 2 (1–2) | 2 (1–3) | 0 (−1–1) | 0.73 |
Catheter insertion site | 0.81 | ||||
Jugular | 148 (73) | 76 (75) | 72 (71) | 21 / 25 | |
Subclavian | 18 (9) | 8 (8) | 10 (10) | 10 / 8 | |
Femoral | 36 (18) | 17 (17) | 19 (19) | 19 / 17 | |
Catheter utilization | 0.12 | ||||
Dialysis | 37 (18) | 24 (24) | 13 (13) | 12 / 23 | |
Parenteral nutrition | 27 (13) | 14 (14) | 13 (13) | 8 / 9 | |
Other | 138 (68) | 63 (62) | 75 (74) | 27 / 15 | |
Mechanical ventilation duration (days) | 16 (7–25) | 20 (12–29) | 10 (3–19) | − 6 (− 15–-1) | < 0.001 |
Catecholamine infusion duration (days) | 3 (0–6) | 3 (0–6) | 3 (0–6) | 0 (−3–3) | 0.88 |
Shock | 132 (65) | 66 (65) | 66 (65) | 20 / 20 | 1 |
Renal replacement therapy | 60 (30) | 22 (22) | 38 (38) | 11 / 27 | 0.02 |
ICU length of stay | 18 (11–27) | 23 (13–31) | 16 (10–24) | −2 (−11–1) | 0.004 |
Mortality | 63 (31) | 31 (30) | 33 (33) | 16 / 13 | 0.76 |