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Table 3 Distribution of signs and symptoms indicating peripheral nervous system involvement in patients with COVID-19

From: Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings

Signs and symptoms indicating peripheral nervous system involvement No. of patients / Proportion
Smell/taste impairment 746 (52·8%)
Anosmia and ageusia 477
Anosmia/hyposmia 128
Ageusia/dysgeusia 141
Visual impairment 9 (0·6%)
Unspecified decreased visual acuity 8
Complete visual loss 1
Oculomotor impairment 14 (1%)
Ophthalmoparesis 7
Diplopia 3
Anisocoria 1
Bilateral mydriasis 1
Bilateral abducens palsy 1
Unilateral abducens palsy 1
Facial palsy 13 (0·9%)
Bilateral weakness/diplegia 7
Unilateral 6
Other cranial nerve impairment 32 (2·3%)
Glossopharyngeal neuralgia 9
Trigeminal neuralgia 8
Tinnitus 5
Decreased hearing 5
Vasoglossopharyngeal neuralgia 2
Dysphagia 2
Reduced tongue movements/tongue deviation 1
Peripheral neuropathies involving trunk and limbs 353 (24·9%)
Mixed neuropathy 247
Pure sensitive impairment 31
Paresthesia 30
Hypoesthesia 1
Pure motor impairment 40
Areflexia 14
Distal weakness 8
Tetraparesis 7
Gait difficulties/instability 6
Paraparesis 3
Tetraplegia 1
Paraplegia 1
Neuralgia 8
Limb neuralgia 7
Occipital neuralgia 1
Dysautonomia manifestations 27
Nerve roots and plexus disorders 145 (10·3%)
Myopathic involvement 102 (7·2%)
Total patients with PNS signs and symptoms 1414 (100%)