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Table 3 Distribution of signs and symptoms indicating peripheral nervous system involvement in patients with COVID-19

From: Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings

Signs and symptoms indicating peripheral nervous system involvement

No. of patients / Proportion

Smell/taste impairment

746 (52·8%)

Anosmia and ageusia

477

Anosmia/hyposmia

128

Ageusia/dysgeusia

141

Visual impairment

9 (0·6%)

Unspecified decreased visual acuity

8

Complete visual loss

1

Oculomotor impairment

14 (1%)

Ophthalmoparesis

7

Diplopia

3

Anisocoria

1

Bilateral mydriasis

1

Bilateral abducens palsy

1

Unilateral abducens palsy

1

Facial palsy

13 (0·9%)

Bilateral weakness/diplegia

7

Unilateral

6

Other cranial nerve impairment

32 (2·3%)

Glossopharyngeal neuralgia

9

Trigeminal neuralgia

8

Tinnitus

5

Decreased hearing

5

Vasoglossopharyngeal neuralgia

2

Dysphagia

2

Reduced tongue movements/tongue deviation

1

Peripheral neuropathies involving trunk and limbs

353 (24·9%)

Mixed neuropathy

247

Pure sensitive impairment

31

Paresthesia

30

Hypoesthesia

1

Pure motor impairment

40

Areflexia

14

Distal weakness

8

Tetraparesis

7

Gait difficulties/instability

6

Paraparesis

3

Tetraplegia

1

Paraplegia

1

Neuralgia

8

Limb neuralgia

7

Occipital neuralgia

1

Dysautonomia manifestations

27

Nerve roots and plexus disorders

145 (10·3%)

Myopathic involvement

102 (7·2%)

Total patients with PNS signs and symptoms

1414 (100%)