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Table 2 Distribution of signs and symptoms indicating central nervous system involvement in patients with COVID-19

From: Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings

Signs and symptoms indicating central nervous system involvement

No. of patients / Proportion

Diffuse compromise

8129 (91·5%)

Psychiatric symptoms (including anxiety disorders, mood disorders, psychosis, and insomnia)

4981

Headache

1805

Dizziness

527

Consciousness impairment

416

Delirium

340

Nausea/vomiting

16

Nuchal rigidity

4

Non-specific combination of signs and symptoms

40

Focal deficit

410 (4·6%)

Extrapyramidal disorders

279

Corticospinal tract impairment

61

Ataxia

18

Dysarthria

13

Amnesia

12

Aphasia

7

Monoparesis

6

Central facial weakness

5

Myoclonus

5

Homonymous hemianopia

4

Seizures

346 (3·9%)

Non-specified seizures

324

Generalized seizures

9

Non-convulsive status epilepticus

6

Focal seizures

3

Seizure-like events (abnormal involuntary movements)

3

Non-epileptic convulsive syncope

1

Total patients with CNS signs and symptoms

8885 (100%)