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Table 2 Distribution of signs and symptoms indicating central nervous system involvement in patients with COVID-19

From: Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findings

Signs and symptoms indicating central nervous system involvement No. of patients / Proportion
Diffuse compromise 8129 (91·5%)
Psychiatric symptoms (including anxiety disorders, mood disorders, psychosis, and insomnia) 4981
Headache 1805
Dizziness 527
Consciousness impairment 416
Delirium 340
Nausea/vomiting 16
Nuchal rigidity 4
Non-specific combination of signs and symptoms 40
Focal deficit 410 (4·6%)
Extrapyramidal disorders 279
Corticospinal tract impairment 61
Ataxia 18
Dysarthria 13
Amnesia 12
Aphasia 7
Monoparesis 6
Central facial weakness 5
Myoclonus 5
Homonymous hemianopia 4
Seizures 346 (3·9%)
Non-specified seizures 324
Generalized seizures 9
Non-convulsive status epilepticus 6
Focal seizures 3
Seizure-like events (abnormal involuntary movements) 3
Non-epileptic convulsive syncope 1
Total patients with CNS signs and symptoms 8885 (100%)