Association of serum antibodies against the Mycobacterium avium complex and hemoptysis: a cross-sectional study

BMC Infectious Diseases

Table 1 Mean values or frequencies of demographic and clinical characteristics according to MAC-Ab presence

Variables	Seronegative group	Seropositive group	P value
Variables	(n = 46)	(n = 109)	P value
Male gender (%)	43.5	18.3	0.001
Age (years)	72 (10)	73 (11)	0.61
BMI (kg/m²)	19.7 (3.0)	18.6 (3.1)	0.06
NTM species
^aMycobacterium avium (%)	58.7	73.4	0.07
^aMycobacterium intracellulare (%)	50.0	35.8	0.10
Isolation of multiple species of NTM (%)	23.9	13.8	0.12
Appearance on computed tomography
Nodular bronchiectatic disease (%)	80.4	70.6	0.10
Fibrocavitary disease (%)	17.4	29.4
Others (%)	2.2	0.0
Antibiotic treatment for MAC disease (%)	54.3	61.5	0.41
Anticoagulant and/or antiplatelet medication (%)	13.0	5.5	0.11

The seropositive and seronegative groups were defined as the subjects with MAC-Ab levels of ≥0.7 U/ml and < 0.7 U/ml, respectively. Values are given as mean with standard deviations in brackets for continuous variables and as percentages for dichotomized and categorical variables. P value denotes the statistical significance of the difference in each variable between seronegative and seropositive groups
MAC-Ab antibody against the Mycobacterium avium complex, BMI body mass index, NTM nontuberculous mycobacteria
^aPatients from whom both Mycobacterium avium and Mycobacterium intracellulare were isolated (n = 14) were included

ISSN: 1471-2334