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Table 3 Total number of HFMD case reduction in I3* under different coverage scenarios over 1 year

From: The burden of hand, foot, and mouth disease among children under different vaccination scenarios in China: a dynamic modelling study

Bivalent vaccine coverage

EV-71 vaccine coverage

0%

10%

30%

50%

80%

Case reduction (%**)

NNV***

Case reduction (%)

NNV

Case reduction (%)

NNV

Case reduction (%)

NNV

Case reduction (%)

NNV

0%

0(0.0)

123,776(7.6)

77.6

339,672(20.9)

84.8

537,032(33.0)

89.4

797,262(49.1)

96.3

10%

130,639(8.0)

73.5

240,476(14.8)

79.8

446,345(27.5)

86.0

633,389(39.0)

90.9

877,700(54.0)

98.4

30%

357,871(22.0)

80.5

457,647(28.2)

83.9

642,969(39.6)

89.6

808,968(49.8)

94.9

1,021,084(62.8)

103.4

50%

563,164(34.7)

85.2

652,564(40.2)

88.3

816,793(50.3)

94.0

961,374(59.2)

99.9

1,141,319(70.2)

109.3

80%

828,560(51.0)

92.7

901,989(55.5)

95.8

1,034,085(63.6)

102.1

1,146,680(70.6)

108.8

1,280,602(78.8)

119.9

100%

976,602(60.1)

98.3

1,039,339(63.9)

101.6

1,150,320(70.8)

108.5

1,242,653(76.5)

115.9

1,349,720(83.0)

128.0

  1. *I3 indicates the number of EV71 or CVA16 HFMD \( \left({\mathrm{I}}_{\mathrm{h}}^{\mathrm{ec}}\right) \) / only EV71- HFMD \( \left({\mathrm{I}}_{\mathrm{h}}^{\mathrm{e}}\right) \), based on different types of vaccines.
  2. **%: The percentage of the number of HFMD case reduction in I3 based on the initial number with no intervention
  3. ***NNV The number of persons needed to be vaccinated per case reduction