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Table 3 Linear regression analysis of CSF cytokine in different time and clinical outcome

From: A preliminary study on the characteristics of Th1/Th2 immune response in cerebrospinal fluid of AIDS patients with cryptococcal meningitis

Cytokine

Item

β (95% CI)

Wald χ2

P value

IL-2

Time

   
 

Baseline

0a

  
 

Week 2

−0.079(−0.141,-0.017)

6.190

0.013

 

Week 4

−0.044(−0.145,0.058)

0.711

0.399

 

Outcome

   
 

Survival

0a

  
 

Death

0.030(−0.044,0.104)

0.622

0.430

IL-13

Time

   
 

Baseline

0a

  
 

Week 2

−1.039(−1.910,-0.168)

5.466

0.019

 

Week 4

2.137(−3.364,7.638)

0.580

0.446

 

Outcome

   
 

Survival

0a

  
 

Death

−1.475(−3.066,0.116)

3.304

0.069

IL-17A

Time

   
 

Baseline

0a

  
 

Week 2

−0.209(−0.360,-0.058)

7.327

0.007

 

Week 4

−0.145(−0.311,0.021)

2.929

0.087

 

Outcome

   
 

Survival

0a

  
 

Death

0.239(−0.038,0.516)

2.849

0.091

VEGF-A

Time

   
 

Baseline

0a

  
 

Week 2

−0.053(−0.101,-0.005)

4.619

0.032

 

Week 4

−0.103(− 0.196,-0.010)

4.713

0.030

 

Outcome

   
 

Survival

0a

  
 

Death

−0.130(−0.293,0.033)

2.456

0.117

  1. IL Interleukin, VEGF-A Vascular Endothelial Growth Factor A, a Set to zero because this parameter is redundant