Identifying risk factors for late HIV diagnosis and survival analysis of people living with HIV/AIDS in Iran (1987–2016)

Table 3 Cox regression analyses of factors associated with survival in newly diagnosed people living with HIV/AIDS in Iran (1987–2016)

Variable	Unadjusted Hazard Rate	95% CI	p-value	Adjusted Hazard Rate	95% CI	p-value
Baseline CD4			< 0.001			< 0.001
> 350	Reference			Reference
< 350	2.25	1.89–2.67		2.21	1.84–2.64
Age (year)			< 0.001			< 0.001
< 30	Reference			Reference
30–40	1.34	1.10–1.62		1.01	0.83–1.23
40–50	1.95	1.57–2.43		1.36	1.08–1.72
> 50	2.29	1.73–3.04		1.81	1.33–2.88
Sex			< 0.001			< 0.001
Female	Reference			Reference
Male	3.20	2.53–4.04		1.76	1.28–2.42
Marital Status			< 0.001			0.002
Single	Reference			Reference
Married	0.65	0.55–0.78		0.86	0.71–1.04
Divorce	1.23	0.99–1.53		1.08	0.86–1.35
Widow	0.87	0.63–1.22		1.68	1.14–2.47
Unknown	1.30	0.74–2.26		1.45	0.82–2.55
Education			< 0.001			0.036
Academic	Reference			Reference
Illiterate	2.27	1.38–3.45		1.47	0.88–2.45
Primary School	2.09	1.34–3.29		1.49	0.93–2.38
Secondary School	1.93	1.23–3.02		1.30	0.82–2.07
High School	1.41	0.88–2.24		1.09	0.67–1.76
Unknown	1.58	0.98–2.54		1.08	0.66–1.76
Transmission Way			< 0.001			< 0.001
Mother to child	Reference			Reference
Injecting drug users	3.75	1.77–7.90		1.87	0.86–4.08
Unprotected sexual	1.13	0.53–2.43		1.01	0.45–2.24
Blood transfusion	1.65	0.75–3.66		1.08	0.46–2.40
Unknown	17.25	11.01–32.45		18.24	7.06–37.09
Year of HIV Diagnosis			< 0.001			< 0.001
After 2011	Reference			Reference
2006–2011	3.08	2.51–3.78		2.45	1.97–3.04
Before 2006	1.42	1.17–1.72		1.22	0.99–1.49
TB co-infection			< 0.001			< 0.001
No	Reference			Reference
Yes	2.82	2.28–3.49		1.77	1.42–2.21
Job			0.269
Employed	Reference			Reference
Unemployed	1.13	0.93–1.38		–	–	–
Unknown	0.99	0.82–1.21		–	–	–

ISSN: 1471-2334