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Table 4 Logistic regression analyses of potential risk factors of mortality in severe COVID-19 patients

From: Risk factors for secondary hemophagocytic lymphohistiocytosis in severe coronavirus disease 2019 adult patients

  Regression Coefficient OR (Odds Ratio) 95% CI P value
SOFA 0.317 1.373 1.006–1.712 0.005
Lowest leukocyte, ×109/L 0.277 1.319 1.174–1.491 < 0.001
Lowest neutrophils, × 109/L −0.011 0.989 0.976–1.001 0.080
Lowest lymphocyte, ×109/L 0.316 1.372 1.089–1.729 0.007
Lowest prealbumin, g/L −0.012 0.987 0.979–0.994 0.001
Lowest albumin, g/L 0.012 1.013 0.988–1.038 0.300
Peak D-Dimer, mg/L −0.001 0.998 0.991–1.005 0.632
Peak aspartate aminotransferase, U/L −0.004 0.995 0.992–0.997 0.000
Peak blood urea nitrogen, mmol/L 0.0004 1.000 0.989–1.011 0.931
Peak serum creatinine, μg/L 0.001 1.001 0.999–1.003 0.131
Peak Interleukin −6, pg/mL −0.000 0.999 0.998–1.000 0.880
Peak C-reactive protein, mg/L 0.006 1.006 1.000–1.012 0.036
Peak lactate dehydrogenase, U/L 0.003 1.003 1.001–1.005 < 0.001
Peak creatine kinase isoenzyme, U/L 0.003 1.003 0.999–1.008 0.080
Peak Troponin, pg/mL 0.000 0.999 0.999–1.000 0.293
Age, y 0.057 1.059 1.030–1.088 < 0.001
Hscore 98–169 vs ≤98 1.393 4.028 1.553–10.444 0.004
Hscore ≥169 vs ≤98 3.125 22.770 2.227–232.800 0.008
  1. Abbreviations: SOFA Sequential Organ Failure Assessment
  2. P value compare between survivor group vs nonsurvivor group, P < 0.05 means had significantly different