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Table 3 Logistic regression analyses of potential risk factors of Hemophagocytic lymphohistiosytosis (HLH)

From: Risk factors for secondary hemophagocytic lymphohistiocytosis in severe coronavirus disease 2019 adult patients

 

Regression Coefficient

OR (Odds Ratio)

95% CI

P value

SOFA

0.221

1.247

1.010–1.539

0.040

Lowest haemoglobin, g/L

0.003

1.003

0.983–1.023

0.769

Lowest platelet,×109/L

0.008

1.008

1.000–1.015

0.038

Lowest neutrophils, ×109/L

0.025

1.026

0.987–1.066

0.195

Lowest fibrinogen, g/L

0.042

1.043

0.999–1.089

0.052

Lowest prealbumin, g/L

0.006

1.006

0.994–1.017

0.332

Peak D-Dimer, mg/L

−0.004

0.996

0.993–1.00

0.061

Peak aspartate aminotransferase, U/L

−0.000

1.000

0.999–1.001

0.910

Peak serum creatinine, μg/L

−0.002

0.998

0.996–1.000

0.126

Peak triglycerides, mmol/L

−0.300

0.741

0.611–0.900

0.003

Peak ferritin, ng/mL

−0.002

0.998

0.997–0.999

< 0.001

Peak Interleukin −6, pg/mL

−0.000

1.000

0.999–1.000

0.175

Peak C-reactive protein, mg/L

−0.002

0.998

0.990–1.005

0.510

Peak lactate dehydrogenase, U/L

−0.000

1.000

0.999–1.000

0.639

  1. Abbreviations: SOFA Sequential Organ Failure Assessment
  2. P value compare between Hscore ≥169 group vs Hscore <169 group, P < 0.05 means had significantly different