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Table 3 Logistic regression analyses of potential risk factors of Hemophagocytic lymphohistiosytosis (HLH)

From: Risk factors for secondary hemophagocytic lymphohistiocytosis in severe coronavirus disease 2019 adult patients

  Regression Coefficient OR (Odds Ratio) 95% CI P value
SOFA 0.221 1.247 1.010–1.539 0.040
Lowest haemoglobin, g/L 0.003 1.003 0.983–1.023 0.769
Lowest platelet,×109/L 0.008 1.008 1.000–1.015 0.038
Lowest neutrophils, ×109/L 0.025 1.026 0.987–1.066 0.195
Lowest fibrinogen, g/L 0.042 1.043 0.999–1.089 0.052
Lowest prealbumin, g/L 0.006 1.006 0.994–1.017 0.332
Peak D-Dimer, mg/L −0.004 0.996 0.993–1.00 0.061
Peak aspartate aminotransferase, U/L −0.000 1.000 0.999–1.001 0.910
Peak serum creatinine, μg/L −0.002 0.998 0.996–1.000 0.126
Peak triglycerides, mmol/L −0.300 0.741 0.611–0.900 0.003
Peak ferritin, ng/mL −0.002 0.998 0.997–0.999 < 0.001
Peak Interleukin −6, pg/mL −0.000 1.000 0.999–1.000 0.175
Peak C-reactive protein, mg/L −0.002 0.998 0.990–1.005 0.510
Peak lactate dehydrogenase, U/L −0.000 1.000 0.999–1.000 0.639
  1. Abbreviations: SOFA Sequential Organ Failure Assessment
  2. P value compare between Hscore ≥169 group vs Hscore <169 group, P < 0.05 means had significantly different