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Fig. 7 | BMC Infectious Diseases

Fig. 7

From: Infant rhesus macaques as a non-human primate model of Bordetella pertussis infection

Fig. 7

Detection of cytokines in the blood after B. p infection. Serum was collected from all 7 animals 1 day before challenge and 2, 6, 10, 14, 21, and 28 days post challenge for the animals in group 1 that were infected with 2016-CY-41 and 4, 8, 12, 16, 23, and 30 days post-challenge for the transmission macaques in group 2 that were cohoused with challenged animals. An unpaired t-test was used to test for differences between pre-infection serum cytokine levels and peak serum cytokine levels obtained at 2–30 dpi with B.p strain 2016-CY-41 since the starting concentrations were highly variable between animals, as was the day of the peak serum cytokine response. *, P < 0.05; **, P < 0.01 vs. pre-challenge; Student’s t-test. The bars with error bars represent the means ± SDs (n = 7)

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