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Table 4 Association between HLA-G genotypes and risk factors for HPV infection recorded by the baseline questionnaire

From: HLA-G polymorphism impacts the outcome of oral HPV infections in women

Risk factors

HLA-G genotype

OR (95% CI)

*010101:010101

*010101:010102

*010101:010103

*010101:010401

*010102:010102

*010102:010401

Miscarriages (≥1) (n = 39)

0.81 (0.37–1.75)

1.13 (0.53–2.42)

1.39 (0.38–5.10)

0.50 (0.15–1.73)

2.18 (0.42–11.24)

0.70 (0.09–5.67)

Infertility (n = 24)

1.09 (0.45–2.66)

1.13 (0.45–2.85)

0.70 (0.09–5.51)

0.24 (0.03–1.84)

1.54 (0.18–13.07)

5.06 (1.22–21.02)

Infertility treatments (n = 15)

0.54 (0.15–1.95)

1.36 (0.45–4.13)

1.17 (0.14–9.52)

0.42 (0.05–3.28)

NC

9.07 (2.08–39.50)

Sexually transmitted diseases (n = 63)

1.40 (0.78–2.51)

0.68 (0.35–1.33)

1.08 (0.34–3.37)

0.59 (0.24–1.48)

0.44 (0.05–3.52)

0.89 (0.19–4.22)

Warts

 Genital (n = 80)

0.62 (0.34–1.12)

1.18 (0.66–2.11)

0.53 (0.15–1.89)

1.88 (0.94–3.77)

0.85 (0.17–4.29)

0.72 (0.15–3.55)

 Oral (n = 8)

NC

4.85 (1.13–20.85)

6.00 (1.11–32.46)

NC

NC

NC

 Skin (n = 166)

0.96 (0.59–1.56)

1.29 (0.77–2.14)

1.98 (0.73–5.35)

0.69 (0.37–1.32)

0.87 (0.25–3.08)

0.18 (0.04–0.87)

 Allergies (n = 126)

1.07 (0.64–1.77)

0.88 (0.52–1.50)

0.95 (0.34–2.63)

1.13 (0.58–2.20)

2.08 (0.49–8.89)

2.52 (0.62–10.29)

 Atopia (n = 43)

0.62 (0.29–1.32)

1.38 (0.68–2.79)

0.34 (0.04–2.63)

0.59 (0.20–1.74)

1.80 (0.35–9.25)

2.78 (0.67–11.55)

 Vulvovaginitis (n = 48)

1.31 (0.31–5.60)

0.39 (0.05–3.20)

NC

NC

NC

NC

Menarche

 Late (>14 years) (n = 21)

0.96 (0.36–2.59)

0.67 (0.22–2.08)

3.12 (0.81–12.03)

2.37 (0.44–12.66)

NC

1.37 (0.16–11.38)

 Early (<11 years) (n = 7)

1.71 (0.37–7.83)

0.45 (0.05–3.82)

NC

1.01 (0.28–3.64)

NC

NC

Start of labour

 Own contractions (n = 145)

1.11 (0.66–1.87)

0.96 (0.57–1.65)

0.65 (0.24–1.75)

1.12 (0.57–2.18)

0.75 (0.20–2.86)

0.75 (0.20–2.86)

 Rupture of the membranes (n = 52)

1.43 (0.75–2.74)

1.31 (0.67–2.55)

0.26 (0.03–2.03)

0.43 (0.15–1.28)

1.28 (0.26–6.37)

1.28 (0.26–6.37)

 Induction (n = 91)

0.87 (0.50–1.53)

0.79 (0.44–1.41)

1.12 (0.40–3.13)

1.74 (0.89–3.44)

0.57 (0.12–2.81)

0.72 (0.81–4.07)

Labour weeks

 Early (<37 weeks) (n = 8)

1.08 (0.19–5.99)

2.75 (0.54–13.90)

NC

NC

NC

NC

 Late (>40 weeks) (n = 181)

0.82 (0.51–1.33)

0.97 (0.59–1.62)

2.32 (0.81–6.61)

1.30 (0.68–2.50)

0.51 (0.14–1.86)

0.95 (0.28–3.17)

 Abnormal placenta (n = 9)

1.30 (0.30–5.56)

0.89 (0.18.4.51)

5.51 (1.03–29.37)

0.85 (0.10–7.06)

NC

NC

  1. The significant associations are bolded