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Table 1 HLA-G alleles, low-resolution groups and genotypes, as related to genital and oral HPV status1 of the women

From: HLA-G polymorphism impacts the outcome of oral HPV infections in women

 

Genital

Oral

HLA-G

Any HPV

(n = 250)

Single

(n = 119)

Multiple (2+)

(n = 131)

Any HPV

(n = 154)

Single

(n = 120)

Multiple (2+)

(n = 34)

Alleles

 *01:01:01

1.01 (0.46–2.21)

0.84 (0.36–1.98)

1.20 (0.50–2.87)

0.88 (0.48–1.62)

1.01 (0.52–1.97)

0.58 (0.23–1.44)

 *01:01:02

0.94 (0.52–1.70)

0.90 (0.47–1.73)

0.97 (0.52–1.84)

0.83 (0.53–1.31)

0.83 (0.51–1.35)

0.85 (0.40–1.83)

 *01:01:03

0.88 (0.34–2.28)

0.76 (0.26–2.22)

1.00 (0.36–2.74)

1.80 (0.83–3.93)

1.42 (0.61–3.35)

3.32 (1.18–9.34)

 *01:03:01

0.89 (0.18–4.32)

0.94 (0.17–5.29)

0.85 (0.15–4.78)

0.24 (0.05–1.13)

0.15 (0.02–1.23)

0.55 (0.07–4.51)

 *01:04:01

1.02 (0.49–2.12)

1.03 (0.47–2.29)

1.01 (0.46–2.22)

0.57 (0.32–1.02)

0.55 (0.29–1.02)

0.67 (0.26–1.73)

 *01:06

2.29 (0.29–18.28)

3.44 (0.41–28.64)

1.29 (0.13–12.67)

1.76 (0.51–6.15)

1.28 (0.31–5.21)

3.58 (0.76–16.81)

Groups2

 G01:01

1.12 (0.12–10.20)

1.06 (0.09–11.98)

1.17 (0.10–13.20)

0.67 (0.11–4.07)

0.79 (0.11–5.67)

0.44 (0.04–5.00)

 G04:01

1.07 (0.52–2.22)

1.09 (0.49–2.40)

1.06 (0.49–2.32)

0.53 (0.30–0.94)

0.51 (0.28–0.95)

0.62 (0.24–1.61)

Genotypes

 010101:010101

0.80 (0.44–1.47)

0.84 (0.43–1.65)

0.76 (0.39–1.48)

1.86 (1.14–3.04)

2.22 (1.32–3.71)

0.92 (0.39–2.21)

 010101:010102

0.82 (0.44–1.55)

0.71 (0.35–1.44)

0.94 (0.47–1.86)

0.73 (0.44–1.21)

0.80 (0.47–1.37)

0.49 (0.19–1.27)

 010101:010103

1.97 (0.44–8.78)

1.95 (0.40–9.48)

1.99 (0.42–9.53)

1.75 (0.67–4.57)

1.09 (0.36–3.33)

4.44 (1.39–14.20)

 010101:010401

1.01 (0.44–2.31)

0.93 (0.37–1.33)

1.08 (0.45–2.62)

0.46 (0.23–0.89)

0.47 (0.23–0.97)

0.41 (0.12–1.44)

 010102:010102

2.05 (0.25–16.55)

2.92 (0.43–24.86)

1.29 (0.13–12.67)

1.50 (0.41–5.42)

1.28 (0.31–5.21)

2.31 (0.41–13.17)

 010102:010401

2.29 (0.29–18.28)

2.92 (0.34–24.86)

1.73 (0.19–15.85)

1.19 (0.36–3.99)

1.01 (0.27–3.86)

1.84 (0.34–9.90)

  1. 1HPV positivity taken as positive for any HPV type during the 72 months follow-up (part of single or multiple infection), Single infection: always only one HPV type present at the follow-up visits and multiple: two or more HPV types presented during the follow up visits. 2Groups as low resolution for the following alleles G01:01: *010101, *010102, *010103, *010114 and G04:01: *01040 and *010404. Only those HLA-G alleles and genotypes that where > 3% prevalent among the women where included to the analyses. The significant associations are bolded
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BMC Infectious Diseases

ISSN: 1471-2334

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