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Table 2 Laboratory findings of pediatric patients infected with Covid-19, Influenza A and Influenza B

From: Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus

  Covid-19 (N = 248) Influenza A (N = 188) Influenza (N = 149) P Value
Blood routine
 White blood cell count Increase 23 (9.43%) 35 (18.82%) 27 (18.88%) 0.0001
Decrease 13 (5.33%) 26 (13.98%) 18 (12.59%)
 Neutrophil count Increase 33 (13.52%) 67 (37.02%) 39 (27.46%) < 0.0001
Decrease 13 (5.33%) 13 (7.18%) 10 (7.04%)
 Lymphocyte count Increase 24 (9.84%) 21 (11.60%) 11 (7.75%) 0.0006
Decrease 8 (3.28%) 23 (12.71%) 21 (14.79%)
Hemoglobin (g/L; 110.0–140.0) 128 (120–137.75) 121.5 (112–128) 122 (113–129) < 0.0001
Platelet (×109/L; 100–320) 261.5 (208.5–314.75) 273 (209.5–363.25) 256 (202–337) 0.1707
Neutrophil/ Lymphocyte 1.06 (0.61–1.69) 1.22 (0.64–2.97) 1.31 (0.68–2.46) 0.0059
Blood biochemistry  
 Total bilirubin Increase 15 (6.22%) 11 (6.32%) 5 (3.76%) 0.5525
 Albumin Decrease 12 (4.98%) 25 (14.37%) 28 (13.53%) 0.0022
 Alanine aminotransferase Increase 27 (11.20%) 15 (8.62%) 7 (5.26%) 0.1536
 γ-alkalinephosphatase Increase 12(%4.98) 12 (6.90%) 7 (5.26%) 0.6683
 Aspartate aminotransferase Increase 32 (13.28%) 43 (24.71%) 40 (29.85%) 0.0003
 Alkaline phosphatase Increase 87 (36.10%) 31 (17.82%) 20 (15.04%) < 0.0001
 Blood urea nitrogen Increase 3 (1.24%) 2 (1.18%) 1 (0.76%) 0.9091
Creatinine Increase 12 (4.98%) 0 3 (2.29%) 0.0094
 Lactate dehydrogenase L Increase 54 (22.88%) 74 (44.58%) 58 (44.27%) < 0.0001
 Lactate dehydrogenase isozyme −1 Increase 64 (27.12%) 74 (44.58%) 59 (45.04%) < 0.0001
 Creatine kinase Increase 15 (6.07%) 15 (8.02%) 14 (9.46%) 0.4487
 Creatine kinase isoenzyme –MB Increase 99 (41.95%) 108 (65.06%) 82 (62.60%) < 0.0001
Infection biomarkers
 Hypersensitive troponin T Increase 7 (5.93%) 6 (22.22%) 2 (15.38%) 0.0252
 Ferroprotein Increase 4 (2.82%) 6 (8.11%) 7 (12.50%) 0.0298
 Serum amyloid A Increase 13 (16.46%) 64 (85.33%) 46 (80.70%) < 0.0001
 Erythrocyte sedimentation rate Increase 13 (22.81%) 46 (56.79%) 28 (51.85%) < 0.0001
 Hypersensitive C-reactive protein Increase 40 (18.60%) 93 (56.71%) 69 (40.64%) < 0.0001
 Procalcitonin Increase 5 (2.05%) 4 (2.23%) 1 (0.70%) 0.5328
 D-Dimer Increase 25 (13.81%) 22 (45.83%) 19 (52.77%) < 0.0001
Others pathogen infections  
 Mycoplasma 45 (40.91%) 46 (55.42%) 21 (42.00%) 0.1089
 Cytomegalovirus 4 (3.03%) 6 (3.57%) 9 (7.03%) 0.2296
 Eb virus 3 (1.99%) 7 (4.12%) 3 (2.24%) 04561
 Influenza A 1 (0.91%)    
 Influenza B 4 (3.63%)    
 Legionella pneumoniae 0 1 (1.20%) 0 0.3799