Table 1 Sensitivity of pooling methods
From: Evaluation of pooling of samples for testing SARS-CoV- 2 for mass screening of COVID-19
Pooling methods | Standard method (individual samples) | Sensitivity (%) (95% CI) | False negative (%) | |
|---|---|---|---|---|
Positive | Negative | |||
4-fold pooling | ||||
Positive | 30 | 0 | 75 (61.7–88.3) | 25 |
Negative | 10 | 0 | ||
8-fold pooling | ||||
Positive | 25 | 0 | 62.5 (47.5–77.5) | 37.5 |
Negative | 15 | 0 | ||
4-fold pooling of weak positive samples | ||||
Positive | 10 | 0 | 50 (28.09–71.91) | 50 |
Negative | 10 | 0 | ||
8-fold pooling of weak positive samples | ||||
Positive | 5 | 0 | 2 (6.03–43.97) | 75 |
Negative | 15 | 0 | ||