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Table 1 - Baseline characteristics of cirrhotic patients

From: Liver function following hepatitis C virus eradication by direct acting antivirals in patients with liver cirrhosis: data from the PITER cohort

  HCV/HIV co-infected (N = 108*) HCV mono-infected (N = 1242*)  
Quantitative variables Median IQR Median IQR p**
Age (years) 52.5 50–55 64.0 54–72 < 0.001
ALT (IU/L) 63.0 40.0–91.0 74.0 47.0–115.0 0.01
AST (IU/L) 60.0 44.0–95.0 70.0 47.0–105.0 0.14
Platelets/μL 105,000 74,000–154,000 119,000 86,350–159,000 0.06
Albumin (g/dL) 3.9 3.5–4.2 3.9 3.6–4.2 0.48
Bilirubin (mg/dL) 0.8 0.6–1.3 0.9 0.6–1.1 0.54
INR 1.1 1.0–1.2 1.1 1.0–1.2 0.10
Categorical variables N. % N. % p***
Sex Male 88 81.5 722 58.1 < 0.001
Female 20 18.5 520 41.9  
BMI Underweight 5 4.6 14 1.1 < 0.001
Normal 70 64.8 514 41.4  
Overweight 25 23.2 550 44.3  
Obese 8 7.4 163 13.1  
Alcohol use Never 50 52.1 803 66.0 < 0.001
Current 26 27.1 116 9.5  
Past 20 20.8 297 24.4  
HCV-
genotype
1 (Non subtyped) 5 4.6 36 2.9 < 0.001
1a 33 30.6 170 13.7  
1b 15 13.9 665 53.5  
2 4 3.7 168 13.5  
3 31 28.7 120 9.7  
4 20 18.5 83 6.7  
5 0 0.0 0 0.0  
Diabetes Yes 16 14.8 259 20.9 0.14
No 92 85.2 983 79.2  
HBV
Infection
Anti-HBc+/HBsAg+ 4 3.7 15 1.2 < 0.001
Anti-HBc+/HBsAg- 47 43.5 262 21.1  
No 57 52.8 965 77.7  
Previous
Interferon
Yes 30 27.8 415 33.4 0.23
No 78 72.2 827 66.6  
HCC Yes 1 0.9 78 6.3 0.02
No 107 99.1 1164 93.7  
Esophageal
varices
Yes 18 16.7 270 21.7 0.22
No 90 83.3 972 78.3  
Ascites Yes 10 9.3 81 6.5 0.28
No 98 90.7 1161 93.5  
Previous
decompensation
Yes 15 13.9 133 10.7 0.31
No 93 86.1 1109 89.3  
Child-Pugh
Score
A-5 39 52.7 762 69.5 < 0.001
A-6 14 18.9 242 22.1  
B-7 12 16.2 58 5.3  
B-8 8 10.8 28 2.6  
B-9 0 0.0 6 0.6  
C-10 1 1.4 0 0.0  
  1. *For some variables inconsistencies are due to missing values
  2. **p value Mann–Whitney rank-sum test
  3. ***p value Chi-square test