| Patient | Comorbidities | Active phase treatment | Cumulative Amph B dose in VL active phase | Previous episodes of VL | Time between first VL episode and current active phase | Relapse during follow-up | Time between current active phase and relapse | Total number of VL episodes | Total follow-up |
---|---|---|---|---|---|---|---|---|---|---|
Non-Relapsing | VL01 | Smoker Previous marijuana use Occasional use of alcohol | Amph. B deoxychol 50 mg/day per 12 days followed by Liposomal Amph. B 20 mg/kg | 28.5 mg/kg | No | NA | No | NA | 1 | 12 months |
VL02 | No information | Liposomal Amph. B 20 mg/kg | 20 mg/kg | No | NA | No | NA | 1 | 12 months | |
VL03 | Occasional use of alcohol Positive serology for Chagas Disease | Amph. B deoxychol 50 mg/day per 3 days followed by Liposomal Amph. B 20 mg/kg | 21.7 mg/kg | No | NA | No | NA | 1 | 12 months | |
VL04 | Virchowian hanseniasis ADHD Development delay – infantilized behavior | Amph. B deoxychol 50 mg/day per 4 days followed by Liposomal Amph. B 20 mg/kg | 22 mg/kg | No | NA | No | NA | 1 | 12 months | |
VL05 | Dyslipidemia Past of drug addiction | Amph. B deoxychol - 1000 mga |  | No | NA | No | NA | 1 | Post-treatment | |
VL08 | Arterial hypertension Smoker Alcoholic | Amph. B Lipid Complex 20 mg/kg | 20 mg/kg | No | NA | No | NA | 1 | 12 months | |
VL11 | Alcoholic Ex-smoker Past of schistosomiasis and gonorrhea | Amph. B Lipid Complex 200 mg/day for 4 days followed by Liposomal Amph. B 20 mg/kg (in 7 weeks) | 20 mg/kg | No | NA | No | NA | 1 | 6 months | |
VL12 | Drug addicted | Amph. B deoxychol 150 mg followed by Liposomal Amph. B 20 mg/kg | 23 mg/kg | No | NA | No | NA | 1 | 6 months | |
VL13 | Alcoholic Smoker | Meglumine antimoniate 20 mgSb+ 5/Kg/day for 3 days followed by Liposomal Amph. B 20 mg/kg | 20 mg/kg | No | NA | No | NA | 1 | Post-treatment | |
VL14 | Arterial hypertension Ex-smoker | Liposomal Amph. B 20 mg/kg in7 days | 20 mg/kg | No | NA | No | NA | 1 | Post-treatment | |
Relapsing | VL06 | Arterial hypertension Diabetes mellitus type 2 Metabolic syndrome | Amph. B Lipid Complex 20 mg/kg | 20 mg/kg | Yes (1) | 4 months | No | NA | 2 | 12 months |
VL07 | Occasional use of alcohol | Amph. B Lipid Complex 40 mg/kg | 40 mg/kg | Yes (3) | 15 months | Yes Jan, 2019 | 4 months | 5 | 12 months | |
VL09 | Chronic renal disease Hypersplenim Past of schistosomiasis | Amph. B Lipid Complex 20 mg/kg | 20 mg/kg | Yes (2) | 15 months | Yes Oct, 2019 | 12 months | 4 | 12 months | |
VL10 | Chagasic cardiac insufficiency | Amph. B Lipid Complex 25 mg/kg | 25 mg/kg | No | NA | Yes Feb, 2019 | 4 months | 2 | 6 months | |
VL15 | Ex-smoker Pulmonary hypertension Subclinic hypothyroidism | Liposomal Amph. B 40 mg/kg | 40 mg/kg | Yes (2) | 5 months | No | NA | 3 | Post-treatment |