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Table 1 Baseline characteristics of patient with Cryptococcal Meningitis Diagnosis between 2010 and 2017

From: Ambulatory induction phase treatment of cryptococcal meningitis in HIV integrated primary care clinics, Yangon, Myanmar

Characteristic

Variable

Total (N = 76)a

Demographics

Age

35 (30, 38)

Male gender

48/76 (63%)

History

Concurrent tuberculosis treatment

33/74 (45%)

Concurrent OI (e.g. oesophageal candidiasis, MAC)

27/76 (36%)

IRIS

25/75 (33%)

Symptoms

Headache

47/64 (73%)

Fever

33/59 (56%)

Weight loss

31/60 (52%)

Altered mental state

58/76 (76%)

Signs

Focal neurology

12/51 (24%)

Skin lesions

15/20 (75%)

Abnormal chest examination

5/63 (7.9%)

Investigations

CD4 count- at time of CM

60.0 (31.0, 112.0)

Serum CrAG positive

33/39 (85%)

Split skin smear positive

16/31 (52%)

CSF Opening pressure > 20 cm

35/72 (54%)

CSF India Ink positive

50/70 (73%)

CSF CrAG positive

16/23 (70%)

  1. Abbreviations: CM cryptococcal meningitis, CrAG cryptococcal antigen, CSF cerebrospinal fluid, OI opportunistic infection, IRIS immune reconstitution inflammatory syndrome, MAC Mycobacterium avium complex
  2. an/N (%) or median (25th, 75th percentile)