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Table 1 Summary of results comparing standard multiplex PCR versus rapid PCR testing for influenza

From: Differences in antibiotic and antiviral use in people with confirmed influenza: a retrospective comparison of rapid influenza PCR and multiplex respiratory virus PCR tests

 

Standard Multiplex PCR

(n = 362)

Rapid PCR

(n = 122)

P-value*

Demographics

 Age (median years) (IQR**)

74 (51–84)

69 (43–84)

0.28

Gender

  

0.84

 Male (n) (%)

178 (49%)

62 (51%)

 

 Female (n) (%)

184 (51%)

60 (49%)

 

Charlson Comorbidity Index (median score) (IQR)

1 (0–2)

0 (0–2)

0.09

Deaths (n) (%)

6 (2%)

2 (2%)

0.68

Result availability

 Test result turnaround time (median hours) (IQR)

22.9 (16.8–38.0)

2.6 (2.0–3.8)

< 0.01

Discharged from ED (n) (%)

110 (30%)

33 (27%)

0.56

Inpatient admission (n) (%)

252 (70%)

89 (73%)

 

Length of Stay (LOS)

 Discharged from ED (median days) (IQR)

0.22 (0.15–0.44)

0.25 (0.18–0.31)

0.90

 Inpatient admission (median days) (IQR)

5.32 (2.88–11.01)

5.16 (2.72–8.18)

0.72

Antimicrobial use

  

< 0.01

 Prescribed (n) (%)

241 (67%)

62 (51%)

 

 Not prescribed (n) (%)

121 (33%)

60 (49%)

 

Oseltamivir use

  

0.02

 Prescribed (n) (%)

203 (56%)

84 (69%)

 

 Not prescribed (n) (%)

159 (44%)

38 (31%)

 

High risk patients (n = 380)

n = 286

n = 94

0.03

 Prescribed oseltamivir (n) (%)

180 (63%)

71 (76%)

 

 Not prescribed oseltamivir (n) (%)

106 (37%)

23 (24%)

 
  1. *P-values calculated using χ2 test or Mann-Whitney as appropriate. **IQR interquartile range. ED Emergency Department