Skip to main content

Table 2 Antibody responses against GMZ2 and constituent antigens in relation to malaria and hookworm infections

From: Effect of hookworm infection and anthelmintic treatment on naturally acquired antibody responses against the GMZ2 malaria vaccine candidate and constituent antigens

  

P. falciparum only

Na + Pf (co-infected)

Antibody

Antigen

β (95%CI)

p-Value

β (95%CI)

p-Value

IgG1

GMZ2

0.01 (−0.66, 0.69)

0.967

−0.41 (−1.08. 0.26)

0.233

GLURP-R0

0.39 (−0.33, 1.53)

0.184

0.82 (0.31, 1.51)

0.019

MSP3

−0.26 (− 0.80, 0.28)

0.346

0.23 (− 0.32, 0.78)

0.402

IgG3

GMZ2

0.30 (−0.57, 1.18)

0.495

0.3 (1.04, 1.10)

0.046

GLURP-R0

0.26 (−0.61, 1.14)

0.554

0.61 (−0.38, 1.60)

0.226

MSP3

0.37 (−0.17, 1.72)

0.358

0.24 (−0.53, 1.01)

0.537

IgM

GMZ2

0.13 (−0.26, 0.53)

0.503

0.05 (−.030, 0.40)

0.774

GLURP-R0

0.08 (−0.66, 0.49)

0.771

0.26 (−0.24, 0.78)

0.300

MSP3

−0.01 (− 0.32, 0.29)

0.924

0.13 (− 0.22, 0.49)

0.458

  1. Multivariate multiple linear regression analysis adjusting for age and sex. β Estimated effect of covariate on antibody level, CI Confidence interval, Na Na, Necator americanus, Pf Plasmodium falciparum. Arbitrary antibody unit were log10 transformed. EC group was set as reference for the model. Analysis was done only on pre-treatment data
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us