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Table 2 Antibody responses against GMZ2 and constituent antigens in relation to malaria and hookworm infections

From: Effect of hookworm infection and anthelmintic treatment on naturally acquired antibody responses against the GMZ2 malaria vaccine candidate and constituent antigens

   P. falciparum only Na + Pf (co-infected)
Antibody Antigen β (95%CI) p-Value β (95%CI) p-Value
IgG1 GMZ2 0.01 (−0.66, 0.69) 0.967 −0.41 (−1.08. 0.26) 0.233
GLURP-R0 0.39 (−0.33, 1.53) 0.184 0.82 (0.31, 1.51) 0.019
MSP3 −0.26 (− 0.80, 0.28) 0.346 0.23 (− 0.32, 0.78) 0.402
IgG3 GMZ2 0.30 (−0.57, 1.18) 0.495 0.3 (1.04, 1.10) 0.046
GLURP-R0 0.26 (−0.61, 1.14) 0.554 0.61 (−0.38, 1.60) 0.226
MSP3 0.37 (−0.17, 1.72) 0.358 0.24 (−0.53, 1.01) 0.537
IgM GMZ2 0.13 (−0.26, 0.53) 0.503 0.05 (−.030, 0.40) 0.774
GLURP-R0 0.08 (−0.66, 0.49) 0.771 0.26 (−0.24, 0.78) 0.300
MSP3 −0.01 (− 0.32, 0.29) 0.924 0.13 (− 0.22, 0.49) 0.458
  1. Multivariate multiple linear regression analysis adjusting for age and sex. β Estimated effect of covariate on antibody level, CI Confidence interval, Na Na, Necator americanus, Pf Plasmodium falciparum. Arbitrary antibody unit were log10 transformed. EC group was set as reference for the model. Analysis was done only on pre-treatment data