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Table 2 Cellularity of bronchoalveolar lavage fluid (BALF) and peripheral blood in all patients, survivors, non-survivors and univariate analysis

From: Bronchoalveolar lavage fluid characteristics and outcomes of invasively mechanically ventilated patients with COVID-19 pneumonia in Genoa, Italy

 

All patients

(n = 64)

Survivors

(n = 43)

(67.2%)

Non-survivors

(n = 21)

21 (32.8%)

P

Cellularity of BALF

 Lymphocytes %, median (IQRb)

1 (0.4–3.75)

1 (0.3–2.25)

1 (1–4)

0.502

 Neutrophils %, median (IQR)

70 (37.5–90.5)

71 (46–90.5)

63 (36–83.5)

0.408

 Macrophages %, median (IQR)

20 (7–42)

20 (7–42)

35 (16.5–56.7)

0.194

 TCD3+ %, median (IQR)

92(82–95)

92 (83–94)

89 (79–96)

0.873

 TCD4+ %, median (IQR)

30 (22–46.5)

31 (22–47)

29 (23–39)

0.976

 TCD8+ %, median (IQR)

52 (39.5–62.7)

53 (37–60)

46 (42–64)

0.995

 TCD4+/TCD8+ Ratio

0.6 (0.4–1.2)

0.6 (0.4–1.2)

0.5 (0.3–0.8)

0.495

 B CD19+ %, median (IQR)

2 (1–5)

2.5 (1–5)

1 (1–5)

0.205

 Natural Killer (CD56 + CD16+) %, median (IQR)

3 (2–10)

5 (2–10)

3 (2.7–13.7)

0.618

Peripheral blood values at time of BALFa performing

 Lymphocytes/mmc, median (IQR)

630 (475–1000)

900 (500–1220)

520 (340–622)

0.012

 TCD4+/mmc, median (IQR)

317 (190–534)

358 (236–651)

227 (152–430)

0.100

 TCD8+/mmc, median (IQR)

82 (39–235)

160 (63–267)

44 (29–87)

0.007

 R TCD4+/TCD8+, median (IQR)

4.1 (2–5.5)

3.2 (1.4–5)

5 (3.6–6.4)

0.430

  1. aBALF bronchoalveolar lavage fluid, bIQR interquartile range