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Table 1 Clinical characteristics of the patients infected with mild-to-moderate SARS-CoV-2

From: Clinical and CT features of mild-to-moderate COVID-19 cases after two sequential negative nucleic acid testing results: a retrospective analysis

Variables Total (n = 51) Moderate (n = 31) Mild (n = 20) P
Ever went to Hubei (n,%)     0.539
 Yes 36 (70.6) 23 (74.2) 13 (65.0)  
 No 15 (29.4) 8 (25.8) 7 (35.0)  
Age, years 34.0 (20.0, 44.0) 37.0 (25.0, 48.0) 31.0 (16.0, 37.5) 0.288
Gender (n,%)     0.813
 Male 24 (47.1) 15 (48.4) 9 (45.0)  
 Female 27 (52.9) 16 (51.6) 11 (55.0)  
Incubation time, days 7.5 (1.0, 11.75) 8.0 (1.75, 12.0) 6.5 (0.0, 9.0) 0.361
Time to negative nucleic acid testing, days 3 (2, 7) 2 (4, 8) 2.5 (1.25, 5.5) 0.291
Symptoms at admission
 Fever (n,%) 34 (66.7) 23 (74.2) 11 (55.0) 0.156
 Duration of fever, days 5.0 (2.0, 7.0) 5.0 (2.0, 7.5) 4.0 (2.0, 6.0) 0.772
 Cough (n,%) 31 (60.8) 22 (71.0) 9 (45.0) 0.083
 Expectoration (n,%) 6 (11.8) 4 (12.9) 2 (10.0) 1.000
 Sore throat (n,%) 6 (11.8) 3 (9.7) 3 (15.0) 0.668
 Headache (n,%) 4 (7.8) 1 (3.2) 3 (15.0) 0.287
 Fatigue (n,%) 2 (3.9) 2 (6.5) 0 (0.0) 0.514
 Stuffy and runny nose (n,%) 4 (7.8) 1 (3.2) 3 (15.0) 0.287
 Gastrointestinal reaction (n,%) 5 (9.8) 4 (12.9) 1 (5.0) 0.636
 Chest tightness and dyspnea (n,%) 7 (13.7) 5 (16.1) 2 (10.0) 0.690
Symptoms after two sequential negative nucleic acid testing
 Fever (n,%) 0 (0) 0 (0) 0 (0)
 Cough (n,%) 17 (33.3) 11 (35.5) 6 (30.0) 0.767
 Expectoration (n,%) 7 (13.7) 5 (16.1) 2 (10.0) 0.690
 Sore throat (n,%) 4 (7.8) 3 (9.7) 1 (5.0) 1.000
 Headache (n,%) 2 (3.9) 0 (0.0) 2 (10.0) 0.149
 Fatigue (n,%) 3 (5.9) 1 (3.2) 2 (10.0) 0.553
 Stuffy and runny nose (n,%) 3 (5.9) 0 (0.0) 3 (15.0) 0.055
 Gastrointestinal reaction (n,%) 3 (5.9) 2 (6.5) 1 (5.0) 1.000
 Chest tightness and dyspnea (n,%) 3 (5.9) 1 (3.2) 2 (10.0) 0.553
 Pulse oximeter O2 saturation, % 97.3 ± 0.95 97.1 ± 0.89 97.6 ± 1.00 0.469
 Heart rate, breaths/min 86.7 ± 15.5 85.9 ± 15.7 88.0 ± 15.5 0.938
Disease history
 Bronchial or pulmonary disease (n,%) 4 (7.8) 4 (12.9) 0 (0.0) 0.094
 Other diseases (n,%)a 6 (11.8) 6 (19.6) 0 (0.0) 0.036
Treatment (n,%)b 0.216
 Western medicine 17 (34.7) 11 (35.5) 6 (33.3)  
 Chinese medicine 15 (30.6) 7 (22.6) 8 (44.4)  
 Both 17 (34.8) 13 (41.9) 4 (22.2)  
  1. Chinese medicine: Jin Hua Qing Gan particles, antiviral particles, Xiang Sha Liu Jun pills, etc.
  2. aOther underlying diseases include glioma, nephrectomy, hyperlipidemia, gastric tumours, type 2 diabetes and thyroid cancer, etc.
  3. bWestern medicine: levofloxacin, moxifloxacin, ribavirin, abidol, lopinavir, ritonavir, interferon, thymoxin, chloroquine phosphate, interferon, oseltamivir, etc.