Table 2 Quartile values of cytokine measurements on Day 1 and Day 4 of SAB
Cytokine (pg/ml) | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Overall p-value Persistence | Overall p-value Mortality |
|---|---|---|---|---|---|---|
TNF | ||||||
Day 1 | < 9.54 | 9.54–18.96 | 18.97–36.85 | > 36.85 | < 0.0001 | |
Day 4 | < 6.73 | 6.73–12.57 | 12.58–24.67 | > 24.67 | < 0.0001 | |
IL-10 | ||||||
Day 1 | < 11.11 | 11.11–29.96 | 29.97–118.22 | > 118.22 | 0.002 | |
Day 4 | < 5.49 | 5.49–13.57 | 13.58–28.93 | > 28.93 | < 0.0001 | |
IL-6 | ||||||
Day 1 | < 25.92 | 25.92–69.56 | 69.57–222.65 | > 222.65 | 0.10 | |
Day 4 | < 7.02 | 7.02–19.93 | 19.94–57.20 | > 57.20 | 0.001 | |
IL-8 | ||||||
Day 1 | < 18.00 | 18.00–48.10 | 48.11–128.56 | > 128.56 | 0.06 | |
Day 4 | < 12.94 | 12.94–28.05 | 28.06–68.95 | > 68.95 | < 0.0001 | |
IFNγ | ||||||
Day 1 | < 4.34 | 4.34–9.13 | 9.14–18.69 | > 18.69 | 0.19 | |
Day 4 | < 3.45 | 3.45–7.00 | 7.01–13.25 | > 13.25 | 0.69 | |
IL-1β | ||||||
Day 1 | < 1.21 | 1.21–2.77 | 2.78–3.25 | > 3.25 | 0.50 | |
Day 4 | < 0.83 | 0.83–1.84 | 1.85–3.64 | > 3.64 | 0.87 | |
IL-17 | ||||||
Day 1 | < 1.92 | 1.92–5.07 | 5.08–11.22 | > 11.22 | 0.17 | |
Day 4 | < 1.88 | 1.88–3.75 | 3.76–9.88 | > 9.88 | 0.23 | |