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Table 1 Demographic, epidemiological and clinical data and test results for 11 patients involved in tularemia outbreak in Youzband Village, 2016–2018

From: Francisella tularensis human infections in a village of northwest Iran

Case No. Age/Gender Lymphadenopathy Wound in lymph node Ocular lesion Primary signs date Clinical sign Treatment/Duration Drinking Water Keeping livestock History of tick biting Serum sampling time (at days post onset) Tube agglutination test IgM titre U/ml (ELISA) IgG titre U/ml (ELISA)
1 29/M Pharyngeal N Y Nov. 2016 Eye discharge, chills, sore throat, swollen lymph nodes Clindamycin, Amoxicillin/ 1 week Only Spring Y N 574 1:320 ≥400 235
2 44/F Pharyngeal Ya N Dec. 2016 Enlarged lymph node, Common Cold sign Cefixime, Metronidazole Hydrocortisone ceftriaxone/
2 month
Only Spring Y N 568 1:160 ≥400 190
3 30/F Preauricular N N Nov. 2016 Fever, Chill, Sore throat, weakness, enlarged lymph node Anti TB drugs/ ND Tap water & spring N N 575 1:320 ≥400 170
4 30/F Pharyngeal N N Nov. 2016 Sore Eyes,
enlarged lymph node
Penicillin/ ND Only spring N N 574 1:320 ≥400 84
5 29/F Pharyngeal& Preauricular N N Dec. 2016 Common cold sign, Anorexia Fever, Chill, sore throat, enlarged lymph node Not treated Only Tap water Y N 566 1:40 260 145
6 4/M Preauricular Y N Dec. 2016 Sore throat, enlarged lymph node (Hospitalized) Cephalexin clindamycin clarithromycin ciprofloxacin/ ND Tap water & spring Y N 567 1:320 240 260
7 8/M Inguinal & pharyngeal N N Nov. 2016 Sore throat, skin rash on feet (Hospitalized), enlarged lymph node Betamethasone/ ND Tap water & spring Y N 574 1:160 250 230
8 14/M Pharyngeal Y N Dec. 2016 Common cold sign, enlarged lymph node Not treated Tap water & spring Y Y 569 1:320 95 ≥300
9 31/F Pharyngeal Ya Y Dec. 2016 Common cold sign, sore throat, chill earache, headache, enlarged lymph node, amaurosis, sore eye Not treated Only spring N N 562 1:160 ≥400 92
10 77/F Preauricular N N Nov. 2016 Sore throat, enlarged lymph node (removed by surgery) Not treated Only spring Y N 576 1:160 195 120
11 31/F Pharyngeal N N Feb. 2018 Earache toothache enlarged lymph node Co-amoxiclav/ 2 month Only Tap water Y Y 115 1:80 32 ≤3
  1. Y Yes, N No, Pos. Positive, Neg. Negative, O. Obtained, NT Not Taken, ND Not determined, LNS Lymph node sample, WBS Whole blood sample, SS Serum sample, aDrained pus 1