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Table 1 Cumulative fraction of response to TGC and CMS in combination with FOS against KPC-2-producing K. pneumoniaea

From: Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation

  1. Gray shading indicates ≥90% CFR, and boldface indicates 80 to 90%
  2. FOS fosfomycin, TGC tigecycline, CMS colistin methanesulfonate
  3. aPharmacodynamic target: AUC24/MIC ≥24 for FOS, AUC24/MIC ≥6.93 for TGC and AUC24/MIC ≥60 for CMS
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