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Table 3 Univariate and multivariate analyses showing significant predictive factors of overall mortality (n = 1252)

From: Impact of acute kidney injury on survival in patients with chronic hepatitis C: a retrospective cohort study

Variable Univariate analysis Multivariate analysis
P HR (95% CI) P HR (95% CI)
Male 0.007 1.63 (1.14–2.34) 0.097 1.38 (0.94–2.00)
Age per year < 0.001 1.03 (1.02–1.05) 0.813 1.00 (0.99–1.02)
Platelet per 109/L < 0.001 0.99 (0.98–0.99) 0.590 0.99 (0.99–1.01)
MELD score per point < 0.001 1.17 (1.14–1.20) 0.126 1.06 (0.98–1.14)
Child-Pugh score per point < 0.001 1.85 (1.67–2.05) 0.436 1.08 (0.89–1.30)
SVR < 0.001 0.13 (0.08–0.22) < 0.001 0.33 (0.19–0.59)
Extrahepatic malignancy < 0.001 3.96 (2.35–6.69) < 0.001 4.25 (2.64–6.82)
CH (diagnosis at entry) Reference Reference
 Com-LC < 0.001 2.69 (1.60–4.53) 0.108 1.60 (0.90–2.84)
 Decom-LC or HCC < 0.001 12.13 (8.27–17.79) < 0.001 5.63 (3.39–9.37)
AKI < 0.001 13.60 (8.92–20.73) < 0.001 6.66 (4.26–10.41)
  1. Abbreviations: HR Hazard ratio, CI Confidence interval, MELD score Model for end-stage liver disease score, SVR Sustained virologic response, Com-LC Compensated cirrhosis, Decom-LC Decompensated cirrhosis, HCC Hepatocellular carcinoma, AKI Acute kidney injury
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