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Table 1 Baseline characteristics according to acute kidney injury

From: Impact of acute kidney injury on survival in patients with chronic hepatitis C: a retrospective cohort study

 

All patients (n = 1252)

AKI (n = 285)

No AKI (n = 967)

Age, year a

58.0 (49.0–67.8)

65.0 (54.0–71.0)

57.0 (48.0–66.0)

Male sexa

685 (54.7%)

176 (61.8%)

509 (52.6%)

Hypertension a

321 (25.6%)

112 (39.3%)

209 (21.6%)

Diabetes a

286 (22.8%)

108 (37.9%)

178 (18.4%)

Alcohol > 40 g/day

244 (19.5%)

65 (22.8%)

179 (18.5%)

Diagnosis at entry a

 CH

1008 (80.5%)

186 (18.5%)

822 (81.5%)

 Com-LC

123 (9.8%)

34 (27.6%)

89 (72.4%)

 Decom-LC or HCC

121 (9.7%)

65 (53.7%)

56 (46.3%)

Genotype

 1

545 (43.5%)

108 (37.9%)

437 (45.2%)

 2

603 (48.2%)

150 (52.6%)

453 (46.8%)

 3

101 (8.1%)

26 (9.1%)

75 (7.8%)

 Others

3 (0.2%)

1 (0.4%)

2 (0.2%)

Extrahepatic malignancy a

90 (7.2%)

35 (12.3%)

55 (5.7%)

SVR a

606 (48.4%)

49 (17.2%)

557 (57.7%)

HCV RNA > 600,000 IU/mL

202 (16.1%)

42 (14.7%)

160 (16.5%)

Albumin, g/dL a

4.1 (3.7–4.4)

3.7 (3.1–4.1)

4.2 (3.9–4.5)

Bilirubin, mg/dL a

0.69 (0.50–1.00)

0.77 (0.50–1.25)

0.67 (0.50–0.94)

Platelet, ×109/L a

183.0 (131.0–232.0)

151.0 (102.0–215.0)

190.0 (142.0–233.0)

PT-INR a

1.03 (0.99–1.11)

1.09 (1.02–1.22)

1.01 (0.98–1.09)

Child-Pugh B or C at entry a

112 (8.9%)

66 (58.9%)

46 (41.1%)

MELD score at entry a

7.0 (6.0–8.0)

8.0 (7.0–10.0)

7.0 (6.0–8.0)

Follow-up period (year)

4.2 (2.1–7.9)

4.6 (2.1–8.0)

4.1 (2.0–7.8)

  1. Data are presented as median (interquartile range) for continuous data and percentages for categorical data
  2. Abbreviations: CH Chronic hepatitis, Com-LC Compensated cirrhosis, Decom-LC Decompensated cirrhosis, HCC Hepatocellular carcinoma, SVR Sustained virologic response, HCV Hepatitis C virus, PT-INR Prothrombin time-international normalized ratio, MELD score Model For End-Stage Liver Disease score
  3. a p < 0.05 AKI vs No AKI using the Mann-Whitney U test and Chi-squared test