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Table 3 Antibiotic sensitivity profile of Escherichia coli in the colonization group and invasive infection group [% (n/N)]

From: Epidemiology and antimicrobial susceptibility of invasive Escherichia coli infection in neonates from 2012 to 2019 in Xiamen, China

Antibiotic Colonization group
(n = 843)
Invasive infection group χ2 values P
E. coli-EOD
(n = 66)
E. coli-LOD
(n = 56)
β-lactams Ampicillin 23.49 (198/843) 28.79 (19/66) 25.00 (14/56) 0.981 0.612
Piperacillin 23.84 (201/843) 28.79 (19/66) 26.79 (15/56) 1.000 0.610
Cefazolin 46.26 (390/843) 66.67 (44/66) 57.14 (32/56) 12.073 0.002
Ceftazidime 79.48 (670/843) 95.45 (63/66) 91.07 (51/56) 14.024 0.001
Cefotaxime 58.24 (491/843) 86.36 (57/66) 73.21 (41/56) 24.063 0.000
Cefepime 61.92 (522/843) 87.88 (58/66) 71.43 (40/56) 19.290 0.000
Compound preparations of β-lactam inhibitors Amoxicillin/clavulanic acid 70.23 (592/843) 89.39 (59/66) 73.21 (41/56) 11.148 0.004
Ampicillin/sulbactam 47.57 (401/843) 50.00 (33/66) 55.36 (31/56) 1.370 0.501
Cefoperazone /sulbactam 100.00 (843/843) 100.00 (66/66) 98.21 (55/56)
Piperacillin/tazobactam 95.14 (802/843) 100.00 (66/66) 94.64 (53/56) 3.412 0.184
Carbapenems Imipenem 100.00 (843/843) 100.00 (66/66) 100.00 (56/56)
Meropenem 100.00 (843/843) 100.00 (66/66) 100.00 (56/56)
Quinolones Levofloxacin 74.61 (629/843) 68.18 (45/66) 67.86 (38/56) 2.392 0.303
Ciprofloxacin 69.75 (588/843) 65.15 (43/66) 62.50 (35/56) 1.791 0.412
Aminoglycosides Gentamicin 72.84 (614/843) 78.79 (52/66) 83.93 (47/56) 4.230 0.124
Amikacin 100.00 (843/843) 100.00 (66/66) 100.00 (56/56)
Sulfonamides Compound sulfamethoxazole 52.31 (441/843) 51.52 (34/66) 55.36 (31/56) 0.217 0.892
Other antibiotics Aztreonam 69.51 (586/843) 93.94 (62/66) 83.93 (47/56) 28.223 0.000