Role of interleukin 6 as a predictive factor for a severe course of Covid-19: retrospective data analysis of patients from a long-term care facility during Covid-19 outbreak

Table 2 AUC and optimal cut-offs for evaluated markers of hypoxemia requiring oxygen therapy by receiver operating characteristic curve analysis

marker	AUC	95% CI of AUC	Asymptotic significance
IL-6	0.911	0.819–1	0.0001
CRP	0.887	0.777–0.996	0.0001
Fibrinogen	0.788	0.640–0.936	0.001
D-dimer	5.777	0.409–0.745	0.392
PCT	0.886	0.767–1	0.0001
Total bilirubin	0.712	0.535–0.888	0.036
Creatinine	0.644	0.443–0.846	0.152
AST	0.838	0.701–0.975	0.001
ALT	0.675	0.491–0.858	0.083
LBC	0.777	0.642–0. 912	0.001
NBC	0.728	0.582–0.783	0.007
EBC	0.841	0.730–0.953	0.0001

ALT alanine aminotransferase, AST aspartate aminotransferase, AUC area under curve, 95% CI 95% confidence interval, CRP C-reactive protein, EBC eosinophil blood count, IL-6 interleukin 6, LBC lymphocyte blood count, NBC neutrophil blood count, PCT procalcitonine, Asymptotic significance below 0.5 is regarded as statistically significant

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