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Table 1 Baseline characteristics of patients. Variables are provided as median (25th percentile, 75th percentile)

From: Role of interleukin 6 as a predictive factor for a severe course of Covid-19: retrospective data analysis of patients from a long-term care facility during Covid-19 outbreak

 

No hypoxemia requiring oxygen therapy (n = 26)

Hypoxemia requiring oxygen therapy (n = 19)

p (Mann-Whitney)

Cohen d

Age (years)

81 (73, 87)

87 (80.5, 90)

0.056

0.522

SpO2

0.96 (0.95, 0.97)

0.91 (0.86, 0.94)

<  0.0001

1.563

CCI

5 (4, 6)

7 (6, 8)

<  0.05

1.038

CRP (mg/L)

8.92 (3.223, 17.943)

70.69 (29.59, 142.46)

<  0.0001

1.398

IL-6 (pg/mL)

12.3 (7.3, 20.5)

43.1 (26.3, 116.7)

<  0.0001

1.880

D-dimer (mg/L)

1.215 (0.558, 2.625)

1.58 (0.78, 3.43)

0.198

0.366

Fibrinogen (g/L)

3.6 (3.3, 4.18)

4.45 (3.825, 5.825)

<  0.05

0.869

Procalcitonine (ng/mL)

0.02 (0.02, 0.03)

0.132 (0.048, 0.313)

<  0.0001

1.791

Ferritin (ug/L)

175.9 (94.13, 429.3)

295.18 (149.79, 778.02)

0.125

0.465

AST (ukat/L)

0.355 (0.29, 0.533)

0.755 (0.403, 1.12)

<  0.0001

1.214

ALT (ukat/L)

0.25 (0.16, 0.37)

0.35 (0.26, 0.54)

<  0.05

0.613

Sodium (mmol/L)

140.9 (137.45, 142.675)

139 (133.6, 145.6)

0.830

0.06

Potasium (mmol/L)

4.09 (3.85, 4.36)

3.71 (3.235, 4.503)

0.184

0.386

Glucose (mmol/L)

4.8 (4.2, 5.4)

5.9 (5.1, 7.1)

<  0.01

0.861

Urea (mmol/L)

6.2 (5.4, 7.5)

11 (6, 21.5)

<  0.01

0.794

Creatinine (umol/L)

74.5 (59.25, 101.25)

110.9 (73, 264)

<  0.05

0.729

Total bilirubin (umol/L)

8.75 (6.55, 11.75)

11.95 (9.8, 15.4)

<  0.0001

0.728

WBC (cells/mL)

4880 (4100, 6515)

5640 (4420, 8640)

0.167

0.395

LBC (cells/mL)

1565 (1045, 2083)

860 (580, 1300)

<  0.0001

1.035

NBC (cells/mL)

2680 (2015, 3800)

3890 (2950, 7450)

<  0.05

0.816

MBC (cells/mL)

490 (370, 615)

440 (250, 680)

0.712

0.107

EBC (cells/mL)

110 (30, 190)

10 (0, 30)

<  0.05

1.373

BBC (cells/mL)

20 (10, 37)

10 (10, 20)

0.155

0.398

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, BBC basophil blood count, CCI Charlson Comorbidity Index, CRP C-reactive protein, EBC eosinophil blood count, IL-6 interleukin 6, LBC lymphocyte blood count, MBC monocyte blood count, NBC neutrophil blood count, p probability, SpO2 oxygen saturation, WBC white blood cell blood count