Diagnostic accuracy of symptoms as a diagnostic tool for SARS-CoV 2 infection: a cross-sectional study in a cohort of 2,173 patients

Table 2 Stratified and multivariate analysis of symptomatology of 2137 patients presenting for COVID-19 suspicion

	Stratified analysis			Multivariate analysis^b
Variable	OR	95% CI	P vale^a	OR	95% CI	P vale^a
Fever	2.98	2.47–3.58	< 0.001	1.96	1.58–2.41	< 0.001
Cough	2.73	2.27–3.28	< 0.001	1.95	1.58–2.41	< 0.001
Odynophagia	1.04	0.87–1.24	0.62
Thoracic pain	1.74	1.44–2.11	< 0.001
Asthenia	1.64	1.37–1.97	< 0.001
Myalgia	1.66	1.39–1.98	< 0.001	1.25	1.00–1.56	0.04
Headache	1.14	0.96–1.37	0.11
Rhinorrhea	1.22	1.01–1.48	0.03
Anosmia	3.23	2.52–4.17	< 0.001	2.96	2.27–3.87	< 0.001
Conjunctivitis	0.98	0.76–1.26	0.87
Dyspnea	2.90	2.39–3.51	< 0.001	1.48	1.17–1.87	0.001
O₂S < 93	2.73	1.89–4.00	< 0.001	1.56	1.17–1.87	0.001
Fever and anosmia	4.30	3.05–6.07	< 0.001
Cough and fever	4.44	3.61–5.47	< 0.001	2.79	2.12–3.69	< 0.001
Cough and anosmia	3.45	2.61–4.56	< 0.001	2.48	1.65–3.74	< 0.001
Fever and dyspnea	3.72	2.96–4.67	< 0.001
Anosmia and dyspnea	3.43	2.42–4.86	< 0.001
Fever, cough, anosmia, dyspnea, O₂S < 93	12.19	1.60–92.92	< 0.001

Abbreviations: OR odds ratio, O₂S Oxygen saturation, 95% CI 95% confidence interval
^a P Value estimated with Pearson’s X2 test
^b Multivariate logistic regression of symptomatology adjusted by age, gender and comorbidities

ISSN: 1471-2334