Clinical utility of cerebrospinal fluid vitamin D-binding protein as a novel biomarker for the diagnosis of viral and bacterial CNS infections

Table 1 Characteristics of included patients and CSF analysis

	All patients (n = 302)	CNS infection (n = 90)	non-CNS infection (n = 212)	P
Age (Yr)	31 (1.9–63.0)	25.5 (6.0–55.0)	37.5 (0.3–65.0)	0.950
Patients age < 18	129 (42.72)	38 (42.22)	91 (42.92)	0.924
Males	166 (54.97)	39 (43.33)	127 (59.91)	0.144
CSF analysis
Total protein (g/L)	0.38 (0.30–0.60)	0.64 (0.36–1.05)	0.34 (0.25–0.48)	< 0.001
Glucose (mg/dL)	65.0 (58.0–750.)	63.0 (55.0–74.0)	65.5 (59.0–75.0)	0.063
WBC count (× 109/L)	0 (0–0.02)	0.09 (0.02–0.27)	0 (0–0)	< 0.001
VDBP (μg/mL)	1.00 (1.00–2.00)	3.20 (1.70–5.10)	1.10 (0.80–1.80)	< 0.001

Abbreviations: CNS central nervous system, AST Aspartate Aminotransferase, ALT alanine transaminase, CRP C-reactive protein, CSF cerebrospinal fluid, WBC white blood cells VDBP, vitamin D-binding protein
Data are presented as medians (interquartile range) or numbers (percentages)

ISSN: 1471-2334