Patients with infective endocarditis and history of injection drug use in a Swedish referral hospital during 10 years

Table 3 Aetiology obtained from valve PCR among patients with IDU-IE and non-IDU-IE

	IDU-IE	Non-IDU-IE	P value
Bacteria in valve PCR from cardiac surgery (n (%))	19 (12)	14 (4)	< 0.01
Staphylococcus aureus (MSSA)	15 (9)	2 (1)	< 0.01
CoNS	2 (1)	1 (0)	0.24
Enterococcus faecalis	2 (1)	0 (0)	–
Viridans group streptococci	0 (0)	6 (2)	–

One patient in the IDU-IE group and three patients in the non-IDU-IE group had positive valve PCR (IDU-IE: MSSA; non-IDU-IE: viridans group streptococci, unspecified gram positive bacteria and Streptococcus bovis) and negative blood culture, all other patients with positive valve PCR had positive blood cultures. Among the patients with positive valve PCR had positive blood cultures, the bacteria found in blood culture were the same as those found in valve PCR. Abbreviations: CoNS coagulase negative staphylococci; IDU injection drug use; IE infective endocarditis; MSSA methicillin susceptible Staphylococcus aureus; n number of patients; PCR polymerase chain reaction

ISSN: 1471-2334