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Table 4 Efficiency of a 16S PCR on the patient’s management regarding sample types analyzed including the type of clinical impact

From: Impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

Type of sample

16S PCR

Clinical impact

p-value

Ra

Eb

Ic

Total

Cardiac valve

173

6

7

0

13 (8%)

0.023

Abscess

71

7

3

3

13 (18%)

Bone sample

80

4

1

1

6 (8%)

Soft tissue

67

0

2

0

2 (3%)

Synovial fluid

178

4

4

3

11 (6%)

CSF

119

3

5

0

8 (7%)

Pleural fluid

27

1

2

0

3 (11%)

Sonication fluid

18

4

0

0

4 (22%)

Aqueous humour

57

2

0

0

2 (4%)

Other

16

0

0

0

0

Total

806

31

24

7

62 (8%)

  1. aRationalizing of the antibiotic therapy
  2. bExtended antibiotic therapy
  3. cIntervention
  4. Abbreviations: PCR polymerase chain reaction, CSF cerebrospinal fluid