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Table 4 Efficiency of a 16S PCR on the patient’s management regarding sample types analyzed including the type of clinical impact

From: Impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

Type of sample 16S PCR Clinical impact p-value
Ra Eb Ic Total
Cardiac valve 173 6 7 0 13 (8%) 0.023
Abscess 71 7 3 3 13 (18%)
Bone sample 80 4 1 1 6 (8%)
Soft tissue 67 0 2 0 2 (3%)
Synovial fluid 178 4 4 3 11 (6%)
CSF 119 3 5 0 8 (7%)
Pleural fluid 27 1 2 0 3 (11%)
Sonication fluid 18 4 0 0 4 (22%)
Aqueous humour 57 2 0 0 2 (4%)
Other 16 0 0 0 0
Total 806 31 24 7 62 (8%)
  1. aRationalizing of the antibiotic therapy
  2. bExtended antibiotic therapy
  3. cIntervention
  4. Abbreviations: PCR polymerase chain reaction, CSF cerebrospinal fluid
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