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Table 3 Efficiency of a positive 16S PCR on the patient’s management regarding sample types analyzed

From: Impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

Type of sample Positive 16S PCR Clinical impact Clinical impact (%) p-value
Cardiac valve 80 13 16a 0.002
Abscess 29 13 45
Bone sample 14 6 43
Soft tissue 10 2 20
Synovial fluid 25 11 44
CSF 13 8 62a
Pleural fluid 5 3 60
Sonication fluid 10 4 40
Aqueous humour 5 2 40
Total 191 62 32
  1. aSignificant pairwise comparison (p = 0.044)
  2. Abbreviations: PCR polymerase chain reaction, CSF cerebrospinal fluid
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