MDR-TB Diagnosis by routine program (combined specimens per index case) | Study sputum collected after start of MDR-TB treatment (one specimen per index case) | |||||
---|---|---|---|---|---|---|
n | % of done | % of 308 IC | n | % of done | % of 280 IC | |
MTB detection (from Table 1) | ||||||
Xpert MTB+ | 150 | 98.7 | 48.7 | 141 | 50.7 | 50.4 |
Hain MTBDRplus MTB+ | 211 | 98.6 | 68.5 | 21 | 77.8 | 7.5 |
Liquid or solid culture MTB+ | 179 | 92.7 | 58.1 | 85 | 30.9 | 30.4 |
Any Xpert or Hain or culture MTB+ | 308 | 100.0 | 100.0 | 147 | 52.5 | 52.5 |
RIF susceptibility testing | ||||||
Done by Xpert Hain and/or pheno | 308 | 100.0 | 145 | 51.8 | ||
Resistant by Xpert and/or Hain and/or pheno | 308 | 100.0 | 100.0 | 128 | 88.3 | 45.7 |
Done by Xpert | 150 | 48.7 | 141 | 50.4 | ||
Resistant by Xpert | 148 | 98.7 | 48.1 | 125 | 88.7 | 44.6 |
Done by Hain | 211 | 68.5 | 21 | 7.5 | ||
Resistant by Hain | 209 | 99.1 | 67.9 | 17 | 81.0 | 6.1 |
Done by pheno | 102 | 33.1 | 53 | 18.9 | ||
Resistant by pheno | 102 | 100.0 | 33.1 | 47 | 88.7 | 16.8 |
Done by pheno only | 29 | 9.4 | 3 | 1.1 | ||
INH susceptibility testing | ||||||
Done by Hain and/or pheno | 246 | 79.9 | 69 | 24.6 | ||
Resistant by Hain and/or pheno | 232 | 94.3 | 75.3 | 57 | 82.6 | 20.4 |
Done by Hain | 204 | 66.2 | 21 | 7.5 | ||
Resistant by Hain | 185 | 90.7 | 60.1 | 14 | 66.7 | 5.0 |
Done by pheno | 101 | 32.8 | 54 | 19.3 | ||
Resistant by pheno | 100 | 99.0 | 32.5 | 49 | 90.7 | 17.5 |
Done by pheno only | 42 | 13.6 | 48 | 17.1 | ||
FLQ susceptibility testing | ||||||
Done by Hain and/or pheno | 108 | 35.1 | 41 | 14.6 | ||
Resistant by Hain and/or pheno | 7 | 6.5 | 2.3 | 6 | 14.6 | |
Streptomycin susceptibility testing | ||||||
Done by pheno | 29 | 9.4 | 54 | 19.3 | ||
Resistant by pheno | 11 | 37.9 | 3.6 | 39 | 72.2 | 13.9 |
SLID susceptibility testing | ||||||
Done by Hain and/or pheno | 107 | 34.7 | 42 | 15 | ||
Resistant by Hain and/or pheno | 8 | 7.5 | 2.6 | 5 | 11.9 | 1.8 |