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Table 1 Assessment of additional potential SARS-CoV-2 infections using loss of smell/taste and Oxford ELISA readings (n = 9324 samples) and Abbott CMIA readings (n = 11,342). The previously reported sensitivity of the Oxford ELISA is 99.1% (95%CI 97.8–99.7%) and the Abbott CMIA is 92.7% (90.2–94.8%) [8]

From: Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections

  Oxford ELISA reading
< 4 million
Low negative
4.0–7.9 million
High negative
≥8 million
Positive
Loss of smell/taste reported 326 (4.1%) 59 (13.1%) 426 (47.0%)
Loss of smell/taste not reported 7643 (95.9%) 390 (86.9%) 480 (53.0%)
Total 7969 449 906
Additional estimated number with loss of smell/taste above baseline 40 (9.0%) 389 (42.9%)
  Abbott CMIA reading
< 0.2
Low negative
0.2–1.39
High negative
≥1.4
Positive
Loss of smell/taste reported 358 (3.7%) 106 (15.5%) 518 (47.4%)
Loss of smell/taste not reported 9205 (96.3%) 580 (84.5%) 575 (52.6%)
Total 9563 686 1093
Additional estimated number with loss of smell/taste above baseline 81 (11.8%) 478 (43.7%)
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