Table 2 Progression and clinical outcomes of pyogenic liver abscess
Characteristics | Total (n = 648) | Maximal size of abscess | P value | ||
|---|---|---|---|---|---|
< 5 cm (n = 293) | 5 ~ 10 cm (n = 312) | ≥ 10 cm (n = 43) | |||
Complications | |||||
 Rupture | 18 (2.8) | 6 (2.0) | 8 (2.6) | 4 (9.3) | 0.025 |
 Hematoma | 10 (1.5) | 2 (0.7) | 6 (1.9) | 2 (4.7) | 0.108 |
 Biloma | 13 (2.0) | 5 (1.7) | 5 (1.6) | 3 (7.0) | 0.055 |
 Venous thrombosis | 22 (7.5) | 21 (6.7) | 4 (9.3) | 47 (7.3) | 0.809 |
Extrahepatic manifestations | |||||
 Pulmonary edema | 88 (13.6) | 31 (10.6) | 49 (15.7) | 8 (18.6) | 0.112 |
 Pleural effusion | 207 (31.9) | 73 (24.9) | 110 (35.3) | 24 (55.8) | < 0.001 |
 Ascites | 116 (17.9) | 40 (13.7) | 60 (19.2) | 16 (37.2) | 0.001 |
 Invasive syndrome | 13 (2.0) | 6 (2.0) | 4 (1.3) | 3 (7.0) | 0.044 |
Antibiotic treatment only | 270 (41.7) | 148 (50.5) | 111 (35.6) | 11 (25.6) | < 0.001 |
Invasive procedure | |||||
 Needle aspiration alone | 12 (1.9) | 12 (4.1) | 0 (0.0) | 0 (0.0) | < 0.001 |
 PCD insertion | 366 (56.5) | 133 (45.4) | 201 (64.4) | 32 (74.4) | < 0.001 |
 PCD insertion within 3 days | 269 (41.5) | 91 (31.1) | 149 (47.8) | 29 (67.4) | 0.037 |
 Multiple PCD drainage | 78 (12.0) | 28 (9.6) | 36 (11.5) | 14 (32.5) | < 0.001 |
 Salvage procedure | 235 (36.3) | 65 (22.2) | 143 (45.8) | 27 (62.8) | < 0.001 |
 Duration of drainage, days | 12.6 ± 8.4 | 10.7 ± 5.5 | 12.1 ± 7.3 | 20.6 ± 14.3 | < 0.001 |
Admission days, days | 19.0 ± 12.1 | 17.4 ± 11.6 | 19.7 ± 11.3 | 24.0 ± 18.0 | < 0.001 |
In-hospital expire | 14 (2.2) | 4 (1.4) | 5 (1.6) | 5 (11.6) | < 0.001 |