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Table 1 Demographic and baseline clinical characteristics of patients

From: Maximal diameter of liver abscess independently predicts prolonged hospitalization and poor prognosis in patients with pyogenic liver abscess

Characteristics Total (n = 648) Maximal size of abscess P value
< 5 cm (n = 293) 5 ~ 10 cm (n = 312) ≥ 10 cm (n = 43)
Age, years 65.7 ± 14.6 65.5 ± 14.9 66.4 ± 14.3 62.2 ± 14.7 0.658
Male sex 406 (62.7) 188 (64.2) 190 (60.9) 28 (65.1) 0.668
BMI, kg/m2 23.8 ± 3.5 23.7 ± 3.4 24.0 ± 3.5 23.1 ± 3.7 0.850
Significant alcohol drinking 58 (9.0) 29 (9.9) 25 (8.0) 4 (9.3) 0.717
Underlying disease
 Malignancy 95 (14.7) 48 (16.4) 41 (13.1) 6 (14.0) 0.525
 Biliary disease 170 (26.2) 81 (27.6) 81 (26.0) 8 (18.6) 0.448
 Diabetes mellitus 183 (28.2) 85 (29.0) 82 (26.3) 16 (37.2) 0.304
 Hypertension 212 (32.7) 101 (34.5) 102 (32.7) 9 (20.9) 0.210
 Chronic liver disease 32 (4.9) 15 (5.1) 14 (4.5) 3 (7.0) 0.765
 Previous liver abscess 10 (1.5) 5 (1.7) 5 (1.6) 0 (0.0) 0.693
Vital sign at admission
 Decreased mentality 16 (2.6) 8 (2.9) 8 (2.7) 0 (0.0) 0.560
 Systolic BP, mmHg 117.4 ± 22.5 118.6 ± 23.1 116.2 ± 21.8 117.5 ± 23.0 0.314
 Diastolic BP, mmHg 71.5 ± 13.0 72.2 ± 13.1 70.7 ± 13.1 72.4 ± 12.4 0.391
Body temperature, °C 37.3 ± 1.0 37.4 ± 1.1 37.2 ± 0.9 37.2 ± 0.9 0.003
 Heart rates, /min 88.2 ± 16.2 88.3 ± 16.1 87.7 ± 16.2 91.5 ± 16.7 0.647
 Respiratory rates, /min 19.3 ± 2.0 19.3 ± 2.0 19.2 ± 2.1 19.6 ± 2.0 0.799
Laboratory findings
WBC, /mm3 13.8 ± 6.9 13.0 ± 7.3 14.0 ± 6.3 16.7 ± 6.9 0.001
Hemoglobin, g/dL 12.0 ± 2.0 12.2 ± 2.0 11.9 ± 1.9 11.0 ± 2.0 0.001
Platelet, × 1000/mm3 273.3 ± 221.8 239.6 ± 140.4 303.4 ± 283.5 285.1 ± 134.4 0.009
ESR, mm/hr 65.9 ± 31.7 59.2 ± 31.2 70.4 ± 30.4 77.1 ± 35.6 < 0.001
PT, INR 1.2 ± 0.2 1.2 ± 0.2 1.2 ± 0.2 1.3 ± 0.1 0.001
 Na, mmol/L 135.7 ± 4.6 135.7 ± 4.6 135.8 ± 4.6 134.6 ± 4.7 0.542
AST, IU/L 94.8 ± 152.0 87.6 ± 147.6 93.0 ± 148.0 157.8 ± 194.6 0.040
ALT, IU/L 83.8 ± 105.3 80.0 ± 109.5 80.3 ± 88.2 134.2 ± 163.8 0.045
Total bilirubin, mg/dL 1.4 ± 1.6 1.6 ± 1.9 1.3 ± 1.3 1.2 ± 1.0 0.029
Albumin, g/dL 3.4 ± 0.5 3.5 ± 0.5 3.3 ± 0.5 3.0 ± 0.4 < 0.001
 Creatinine, mg/dL 1.0 ± 0.9 1.0 ± 0.8 1.0 ± 0.9 1.0 ± 1.2 0.637
 LD, IU/L 582.0 ± 297.9 569.8 ± 303.3 576.7 ± 298.3 694.4 ± 240.5 0.110
hs-CRP, mg/L 160.3 ± 84.6 139.8 ± 85.3 174.9 ± 81.0 193.3 ± 75.2 < 0.001
PCT, ng/mL 17.4 ± 28.6 19.9 ± 30.2 17.3 ± 28.8 4.6 ± 9.3 0.042
CT findings
Non-single lesion 166 (25.6) 88 (30.0) 73 (23.4) 5 (11.6) 0.016
Cystic appearance 334 (51.5) 99 (33.8) 198 (63.5) 37 (86.0) < 0.001
Multiloculated abscess 391 (60.3) 119 (40.6) 239 (76.6) 33 (76.7) < 0.001
  1. Data were expressed as number (percentage) or mean ± standard deviation. BMI Body mass index, BP Blood pressure, WBC White blood cell, ESR Erythrocyte sedimentation rate, PT Prothrombin time, Na Sodium, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LD Lactate dehydrogenase, hs-CRP High sensitivity C-reactive protein, PCT Procalcitonin, CT Computed tomography
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