Table 2 Unweighted incidence rates of COVID-19-Like Symptoms (CLS) by covariate values and univariable hazard-ratios^a

  < 40

732/8561

8.55 (7.94; 9.19)

Reference

 [40–50[

783/10,980

7.13 (6.64; 7.65)

0.87 (0.78; 0.96)

0.0053

 [50–60[

619/10,912

5.67 (5.23; 6.14)

0.68 (0.61;0.75)

< 0.0001

 [60–70[

480/12,120

3.96 (3.61; 4.33)

0.43 (0.38;0.48)

< 0.0001

  > =70

421/19,526

2.16 (1.96; 2.37)

0.27 (0.23; 0.31)

< 0.0001

 Female

1937/40,626

4.77 (4.56;4.99)

reference

 Male

1098/21,473

5.11 (4.82; 5.43)

0.88 (0.81; 0.95)

0.0011

 Ile-de-France

697/11,081

6.29 (5.83; 6.78)

1.38 (1.27; 1.51)

< 0.0001

 GrandEst

286/4908

5.83 (5.17; 6.54)

1.30 (1.15; 1.48)

< 0.0001

 Other French metropolitan regions

2052/46,110

4.45 (4.26; 4.65)

reference

 Rural

539/14,249

3.78 (3.47; 4.12)

Reference

  < 20,000 inhab.

386/10,069

3.83 (3.46; 4.24)

1.07 (0.94; 1.22)

0.2903

 20–000-100,000

465/10,114

4.60 (4.19; 5.04)

1.23 (1.09; 1.40)

0.0010

  > 100,000 inhab.

1581/26,458

5.98 (5.68; 6.28)

1.26 (1.12; 1.41)

< 0.0001

 Missing

64/1209

5.29 (4.08; 6.76)

 Nb persons (incl. participant)

  1

495/10,881

4.55 (4.16; 4.97)

Reference

  2

1076/29,241

3.68 (3.46; 3.91)

0.81 (0.73; 0.91)

0.0002

  3 or +

1453/21,496

6.76 (6.42; 7.12)

1.36 (1.23; 1.51)

< 0.0001

  Missing

11/481

2.29 (1.14; 4.09)

 Nb children (< 18 yrs)

  0

1881/46,600

4.04 (3.86; 4.22)

Reference

< 0.0001

  1 or +

1143/15,018

7.61 (7.18; 8.07)

1.77 (1.64; 1.91)

  Missing

11/481

2.29 (1.14; 4.09)

  < High-school degree

275/7178

3.83 (3.39; 4.31)

Reference

 High-school degree or undergraduate

1311/26,739

4.90 (4.64; 5.18)

1.35 (1.19; 1.54)

< 0.0001

 Graduate degree or doctorate

1147/22,155

5.18 (4.88; 5.49)

1.56 (1.37; 1.78)

< 0.0001

 Missing

302/6027

5.01 (4.46; 5.61)

Professional activity before lockdown

 Student

36/446

8.07 (5.65; 11.2)

1.18 (0.85; 1.64)

0.3221

 Working

2025/30,170

6.71 (6.42; 7.01)

Reference

 Looking for a job

113/1578

7.16 (5.90; 8.61)

1.01 (0.84; 1.22)

0.8955

 Retired

740/27,739

2.67 (2.48; 2.87)

0.43 (0.39; 0.47)

< 0.0001

 Not working due to health conditions

48/529

9.07 (6.69; 12.0)

1.35 (1.01; 1.79)

0.0415

 No professional activity (housewife or husband)

62/1490

4.16 (3.19; 5.33)

0.64 (0.50; 0.83)

0.0006

 Missing

11/147

7.50 (3.74; 13.4)

 Healthcare worker (Y vs N)

161/2207

7.29 (6.21; 8.51)

1.44 (1.23; 1.69)

< 0.0001

 Other essential job (Y vs N)

361/5750

6.28 (5.65; 6.96)

1.20 (1.08; 1.35)

0.0010

 Not working

999/31,782

3.14 (2.95; 3.34)

0.56 (0.51; 0.62)

< 0.0001

 Stopped working

173/2321

7.45 (6.38; 8.65)

1.12 (0.95; 1.32)

0.1691

 Working from home, remote working

959/15,052

6.37 (5.97; 6.79)

Reference

 Partially working from home

188/3143

5.98 (5.16; 6.90)

0.97 (0.83; 1.14)

0.7257

 Working outside home

313/4573

6.84 (6.11; 7.65)

1.12 (0.99; 1.27)

0.0835

 Other

68/951

7.15 (5.55; 9.07)

1.07 (0.83; 1.36)

0.6136

 Missing

335/4277

7.83 (7.02; 8.72)

  < 18.5

104/2035

5.11 (4.18; 6.19)

1.15 (0.94; 1.40)

0.1746

 [18.5; 25[

1621/35,552

4.56 (4.34; 4.79)

Reference

 [25; 30[(overweight)

826/16,650

4.96 (4.63; 5.31)

1.08 (0.99; 1.17)

0.0763

  > =30 (obese)

365/5615

6.50 (5.85; 7.20)

1.40 (1.25; 1.56)

< 0.0001

 Missing

119/2247

5.30 (4.39; 6.34)

 Yes

1005/20,670

4.86 (4.57; 5.17)

1.12 (1.03; 1.21)

0.0053

 No

1993/40,834

4.88 (4.67; 5.10)

Reference

 Didn’t know

34/461

7.38 (5.11; 10.3)

1.73 (1.23; 2.43)

0.0015

 Missing

3/135

2.23 (0.46; 6.51)

 Asthma, COPD, other resp. diseases

415/8319

4.99 (4.52; 5.49)

1.51 (1.35; 1.69)

< 0.0001

 Diabetes

113/3582

3.15 (2.60; 3.79)

1.00 (0.83; 1.22)

0.9662

 Hypertension

270/6780

3.98 (3.52; 4.49)

0.92 (0.81; 1.04)

0.1682

 Other cardiovascular diseases

79/2194

3.60 (2.85; 4.49)

0.88 (0.70; 1.10)

0.2493

 Cancer

168/3286

5.11 (4.37; 5.95)

1.14 (0.97; 1.34)

0.1078

 Anxiety, depression

132/1702

7.75 (6.49; 9.20)

1.72 (1.44; 2.04)

< 0.0001

 Other

432/8003

5.40 (4.90; 5.93)

1.27 (1.15; 1.41)

< 0.0001

 Missing

3/135

2.23 (0.46;6.51)

(Y vs N)

58/207

28.0 (21.2; 36.1)

5.68 (4.38; 7.37)

< 0.0001