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Table 2 Association between parenchymal CT extension and laboratory data

From: The association between clinical laboratory data and chest CT findings explains disease severity in a large Italian cohort of COVID-19 patients

 

CT lesion extension

 
 

< 20% (n = 339)

20–40% (n = 340)

40–60% (n = 120)

> 60% (n = 67)

 
 

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

P

White blood cells (10^9/L)

304

4.79 (3.84–5.91)

315

5.11 (4.02–6.50)

113

5.60 (4.33–7.85)

66

6.22 (4.66–7.97)

0.0005

Neutrophils (10^9/L)

265

3.02 (2.32–4.04)

291

3.64 (2.66–4.76)

101

4.13 (3.05–6.16)

62

4.79 (3.49–6.49)

< 0.0001

Lymphocytes (10^9/L)

264

1.14 (0.86–1.57)

290

1.05 (0.77–1.39)

100

0.89 (0.68–1.29)

62

0.85 (0.63–1.05)

0.0004

Platelets (10^9/L)

301

180.00 (146.51–221.25)

313

176.00 (147.29–218.75)

113

180.00 (140.19–218.25)

65

214.00 (159.00–269.25)

0.0086

Prothrombin time (ratio)

29

1.00 (0.96–1.05)

55

1.10 (1.02–1.15)

37

1.08 (1.02–1.19)

25

1.10 (1.05–1.14)

0.1367

C-reactive protein (mg/L)

299

15.00 (7.02–29.73)

315

43.02 (24.03–85.38)

112

84.60 (46.68–135.66)

64

122.50 (49.55–206.40)

< 0.0001

Procalcitonin (μg/L)

59

0.090 (0.05–0.12)

75

0.13 (0.09–0.20)

46

0.18 (0.11–0.41)

27

0.26 (0.11–0.60)

0.6363

Creatinine (μmol/L)

90

75.60 (67.20–91.96)

109

84.88 (67.91–95.67)

59

88.42 (74.36–114.95)

33

92.84 (79.14–128.21)

0.0162

AST (U/L)

68

28.50 (23.20–36.00)

90

38.50 (29.00–49.00)

58

43.00 (34.00–62.28)

29

45.00 (40.00–52.95)

< 0.0001

ALT (U/L)

71

25.00 (19.25–39.50)

93

30.73 (19.00–43.50)

57

32.00 (23.54–41.11)

29

30.00 (23.22–39.50)

0.0091

Total bilirubin (μmol/L)

63

8.55 (6.84–11.97)

86

10.26 (8.48–13.68)

51

10.26 (6.84–13.68)

30

11.12 (8.55–17.10)

0.9055

Albumin (g/L)

14

40.90 (38.30–42.20)

30

38.60 (36.30–41.20)

25

37.50 (35.55–39.52)

13

38.30 (32.63–40.10)

0.0077

LDH (U/L)

249

408.50 (358.15–487.00)

273

510.53 (422.77–599.75)

88

639.50 (474.85–783.50)

49

707.00 (496.81–896.50)

< 0.0001

PCO2 (mmHg)

73

35.70 (32.58–38.35)

86

34.40 (31.00–37.20)

53

33.30 (30.88–36.45)

31

36.30 (32.15–42.08)

0.6574

PO2 (mmHg)

73

79.50 (69.33–87.05)

85

71.00 (64.20–78.40)

53

65.50 (61.68–74.42)

31

60.80 (54.63–72.65)

0.0014

SO2 (%)

284

96.50 (95.00–97.80)

286

95.20 (93.80–96.50)

103

93.70 (91.80–95.78)

62

91.80 (88.30–94.40)

< 0.0001

  1. P: p-value for coefficient of CT variable in a multiple linear regression controlled for confounders age and sex