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Table 1 Summary of demographic, clinical variables and CT findings

From: The association between clinical laboratory data and chest CT findings explains disease severity in a large Italian cohort of COVID-19 patients

   Parenchymal extension  
   < 20% 20–39% 40–59% ≥60% Fisher’s exact test p-value
Demographic and clinical variables
 Age ≥60 y (n = 432) 133 (39.2) 175 (51.5) 82 (68.3) 42 (62.7) < 0.0001
< 60 y (n = 434) 206 (60.8) 165 (48.5) 38 (31.7) 25 (37.3)
 Sex Male (n = 527) 185 (54.6) 205 (60.3) 88 (73.3) 49 (73.1) 0.0001
Female (n = 339) 154 (45.4) 135 (39.7) 32 (26.7) 18 (26.9)
 Charlson comorbidity index ≥1 (n = 151) 50 (15.7) 48 (15.0) 28 (24.8) 25 (37.9) < 0.0001
0 (n = 667) 268 (84.3) 273 (85.0) 85 (75.2) 41 (62.1)
 Hospitalization N (n = 503) 255 (75.2) 197 (57.9) 37 (30.8) 14 (20.9) < 0.0001
Y (n = 363) 84 (24.8) 143 (42.1) 83 (69.2) 53 (79.1)
 Death within 30 days N (n = 773) 322 (95.0) 317 (93.2) 96 (80.0) 38 (56.7) < 0.0001
Y (n = 93) 17 (5.0) 23 (6.8) 24 (20.0) 29 (43.3)
CT findings
 Ground-glass opacities N (n = 29) 26 (7.7) 2 (0.6) 1 (0.8) 0 (0.0) 0.0051
Y (n = 837) 313 (92.3) 338 (99.4) 119 (99.2) 67 (100)
 Consolidation N (n = 319) 152 (44.8) 118 (34.7) 31 (25.8) 18 (26.9) 0.0002
Y (n = 547) 187 (55.2) 222 (65.3) 89 (74.2) 49 (73.1)
 Crazy-paving pattern N (n = 126) 66 (60.6) 38 (33.3) 15 (25.0) 7 (20.6) 0.0042
Y (n = 191) 43 (39.4) 76 (66.7) 45 (75.0) 27 (79.4)
 Enlarged lymph nodes N (n = 279) 104 (95.4) 102 (89.5) 49 (81.7) 24 (70.6) 0.0005
Y (n = 38) 5 (4.6) 12 (10.5) 11 (18.3) 10 (29.4)
 Pleural effusion N (n = 290) 106 (97.2) 104 (91.2) 52 (86.7) 28 (82.4) 0.0101
Y (n = 27) 3 (2.8) 10 (8.8) 8 (13.3) 6 (17.6)
  1. Proportions of demographic/clinical variables and CT findings across CT extension classes [n (% of class column)]. Data for ground glass opacities and consolidation are obtained from the entire cohort (n = 866); raw numbers and frequencies for the other CT categories are calculated from patients observed until March 13 (n = 318)
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