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Table 1 Summary of demographic, clinical variables and CT findings

From: The association between clinical laboratory data and chest CT findings explains disease severity in a large Italian cohort of COVID-19 patients

  

Parenchymal extension

 
  

< 20%

20–39%

40–59%

≥60%

Fisher’s exact test p-value

Demographic and clinical variables

 Age

≥60 y (n = 432)

133 (39.2)

175 (51.5)

82 (68.3)

42 (62.7)

< 0.0001

< 60 y (n = 434)

206 (60.8)

165 (48.5)

38 (31.7)

25 (37.3)

 Sex

Male (n = 527)

185 (54.6)

205 (60.3)

88 (73.3)

49 (73.1)

0.0001

Female (n = 339)

154 (45.4)

135 (39.7)

32 (26.7)

18 (26.9)

 Charlson comorbidity index

≥1 (n = 151)

50 (15.7)

48 (15.0)

28 (24.8)

25 (37.9)

< 0.0001

0 (n = 667)

268 (84.3)

273 (85.0)

85 (75.2)

41 (62.1)

 Hospitalization

N (n = 503)

255 (75.2)

197 (57.9)

37 (30.8)

14 (20.9)

< 0.0001

Y (n = 363)

84 (24.8)

143 (42.1)

83 (69.2)

53 (79.1)

 Death within 30 days

N (n = 773)

322 (95.0)

317 (93.2)

96 (80.0)

38 (56.7)

< 0.0001

Y (n = 93)

17 (5.0)

23 (6.8)

24 (20.0)

29 (43.3)

CT findings

 Ground-glass opacities

N (n = 29)

26 (7.7)

2 (0.6)

1 (0.8)

0 (0.0)

0.0051

Y (n = 837)

313 (92.3)

338 (99.4)

119 (99.2)

67 (100)

 Consolidation

N (n = 319)

152 (44.8)

118 (34.7)

31 (25.8)

18 (26.9)

0.0002

Y (n = 547)

187 (55.2)

222 (65.3)

89 (74.2)

49 (73.1)

 Crazy-paving pattern

N (n = 126)

66 (60.6)

38 (33.3)

15 (25.0)

7 (20.6)

0.0042

Y (n = 191)

43 (39.4)

76 (66.7)

45 (75.0)

27 (79.4)

 Enlarged lymph nodes

N (n = 279)

104 (95.4)

102 (89.5)

49 (81.7)

24 (70.6)

0.0005

Y (n = 38)

5 (4.6)

12 (10.5)

11 (18.3)

10 (29.4)

 Pleural effusion

N (n = 290)

106 (97.2)

104 (91.2)

52 (86.7)

28 (82.4)

0.0101

Y (n = 27)

3 (2.8)

10 (8.8)

8 (13.3)

6 (17.6)

  1. Proportions of demographic/clinical variables and CT findings across CT extension classes [n (% of class column)]. Data for ground glass opacities and consolidation are obtained from the entire cohort (n = 866); raw numbers and frequencies for the other CT categories are calculated from patients observed until March 13 (n = 318)