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Table 3 Factors associated with drug resistance transmission within clusters

From: HIV drug resistance and HIV transmission risk factors among newly diagnosed individuals in Southwest China

Variables

N

Persons in TC

DR in TC

Crude OR (95% CI)

p

Adjusted OR (95% CI)a

p

Age

  < 35 years

508 (44.14)

288 (56.7)

7 (1.4)

1

 

1

 

  ≥ 35 years

643 (55.86)

297 (46.2)

29 (4.5)

4.34 (1.87–10.08)

0.001

3.02 (0.94–9.73)

0.064

Marital status

 Married

479 (41.62)

221 (46.1)

17 (3.5)

1

 

1

 

 Unmarried

534 (46.39)

305 (57.1)

13 (2.4)

0.57 (0.28–1.19)

0.133

4.24 (1.51–11.9)

0.006

 Divorced/widowed

126 (10.95)

50 (39.7)

3 (2.4)

0.77 (0.22–2.72)

0.680

  

 Unknown

12 (1.04)

9 (75.0)

2 (16.7)

6.0 (1.02–35.16)

0.047

6.26 (0.8–49.3)

0.081

Educational level

 College and above

336 (29.19)

203 (60.4)

3 (0.9)

1

 

1

 

 High school/ technical school

225 (19.55)

118 (52.4)

2 (0.9)

0.16 (0.04–0.69)

0.88

1.29 (0.2–8.39)

0.793

 Junior high school/ below

590 (51.3)

264 (44.7)

31 (5.3)

8.87 (2.67–29.45)

0.000

5.89 (1.37–24.97)

0.017

Ethnicity

 Han

601 (52.22)

311 (51.7)

16 (2.7)

1

   

 Zhuang

483 (41.96)

235 (48.7)

16 (3.3)

1.35 (0.66–2.76)

0.409

  

 Other

68 (5.91)

38 (55.9)

4 (5.9)

2.18 (0.69--6.89)

0.186

  

Infection route

 Heterosexual

693 (60.21)

333 (48.1)

32 (4.6)

1

 

1

 

 MSM

405 (35.19)

238 (58.8)

4 (1.0)

6.22 (2.17–17.83)

0.001

1.89 (0.51–6.99)

0.339

 Other

53 (4.60)

14 (26.4)

0 (0.0)

   

Sex

 Male

919 (79.84)

490 (53.3)

28 (3.0)

1

   

 Female

232 (20.16)

95 (40.9)

8 (3.4)

1.52 (0.67–3.44)

0.318

  

Subtype

 CRF01_AE

485 (42.14)

226 (46.6)

12 (2.5)

1

 

1

 

 CRF07_BC

356 (30.93)

218 (61.2)

6 (1.7)

0.51 (0.19–1.37)

0.179

  

 CRF08_BC

183 (15.90)

81 (44.3)

17 (9.3)

4.74 (2.15–10.44)

0.000

3.69 (1.5–9.04)

0.004

 CRF55_01B

79 (6.86)

47 (59.5)

0 (0.0)

   

 Other

48 (4.17)

13 (27.1)

1 (2.1)

1.49 (0.18–12.4)

0.714

  

Year of Diagnosis

 2016

348 (30.23)

168 (48.3)

12 (3.4)

1

   

 2017

422 (36.66)

232 (55.0)

16 (3.8)

0.96 (0.44–2.09)

0.924

  

 2018

381 (33.1)

185 (48.6)

8 (2.1)

0.59 (0.23–1.48)

0.257

  
  1. aAdjusted for age, marital status, educational level, subtype
  2. TC transmission clusters, DR drug resistance, OR odds ratio, CI confidence interval, MSM men who have sex with men, CRF circulating recombinant form