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Table 5 A multivariate analysis of risk factors for COVID-19 severity

From: Renin-angiotensin system modulators and other risk factors in COVID-19 patients with hypertension: a Korean perspective

  Severity grade 1* Severity grade 2† Death‡
Odds Ratio P Odds Ratio P Odds Ratio P
ARB/ACEI use before COVID- 19 diagnosis 1.05 (0.79–1.39) 0.759 0.99 (0.65–1.51) 0.9556 1 (0.63–1.58) 0.9851
ARB/ACEI use after COVID- 19 diagnosis 1.35 (0.83–2.2) 0.2206 0.92 (0.41–2.03) 0.8279 0.5 (0.17–1.44) 0.1978
Age group: 61–69 2.89 (2.13–3.93) 0.0685 3.48 (1.84–6.58) 0.0175 3.38 (1.53–7.46) 0.0033
Age group: 70–79 4.76 (3.47–6.53) 0.0002 7.48 (4.05–13.83) 0.0045 9.99 (4.76–20.99) 0.0008
Age group: ≥80 9.69 (6.9–13.59) <.0001 24.66 (13.48–45.13) <.0001 35.89 (17.31–74.43) <.0001
Female 0.66 (0.53–0.82) 0.0001 0.52 (0.38–0.72) <.0001 0.51 (0.36–0.73) 0.0002
Diabetes mellitus 1.46 (1.17–1.81) 0.0007 1.63 (1.17–2.27) 0.0038 1.79 (1.24–2.57) 0.0018
Cardiovascular disease 0.98 (0.62–1.56) 0.9361 0.93 (0.48–1.78) 0.8206 0.88 (0.43–1.77) 0.7089
Cerebrovascular disease 1.16 (0.87–1.54) 0.3179 1.08 (0.73–1.58) 0.7028 1.23 (0.82–1.84) 0.3121
Ischemic heart disease 0.99 (0.71–1.38) 0.9361 0.97 (0.62–1.53) 0.8956 0.93 (0.57–1.52) 0.7828
COPD 1.44 (0.76–2.69) 0.2611 0.92 (0.41–2.05) 0.8334 1.04 (0.46–2.34) 0.9345
Malignancy 1.17 (0.79–1.73) 0.4253 1.36 (0.82–2.24) 0.2299 1.45 (0.85–2.44) 0.17
Renal replacement
therapy
9.99 (3.82–26.1) <.0001 4.13 (1.31–13.02) 0.0154 5.64 (1.71–18.58) 0.0045
  1. * Severity grade 1(moderate, severe, critical and death cases) was defined as a more serious cases than mild cases. Severity grade 1 was compared with mild cases
  2. † Severity grade 2(severe, critical and death cases) was defined as a more serious cases than moderate cases. Severity 2 grade was compared with mild or moderate cases
  3. ‡ Death cases were compared with mild, moderate, severe, critical cases
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