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Table 2 Baseline characteristics

From: Multiple antimicrobial resistance and outcomes among hospitalized patients with complicated urinary tract infections in the US, 2013–2018: a retrospective cohort study

 

TR

%

non-TR

%

P-value

N = 3040 (13.03%)

N = 20,291 (86.97%)

 

Mean age, years (SD)

66.9 (16.6)

65.1 (18.0)

< 0.001

Gender: male

1752

57.63%

9685

47.73%

< 0.001

Race

 White

2186

71.91%

15,482

76.30%

< 0.001

 Black

543

17.86%

2759

13.60%

 Other

282

9.28%

1919

9.46%

 Unknown

29

0.95%

131

0.65%

 

Hispanic Ethnicity

164

5.39%

1087

5.36%

0.931

Admission Source

 Non-healthcare facility (including from home)

2307

75.89%

16,518

81.41%

< 0.001

 Clinic

201

6.61%

1299

6.40%

 Transfer from SNF, ICF

324

10.66%

1041

5.13%

 Transfer from another non-acute care facility

122

4.01%

779

3.84%

 Other

86

2.83%

654

3.22%

Admission type

 Medical

2724

89.61%

17,890

88.17%

0.021

 Surgical

316

10.39%

2401

11.83%

 

Elixhauser Comorbidities

 Congestive heart failure

705

23.19%

3999

19.71%

< 0.001

 Valvular disease

166

5.46%

1339

6.60%

0.017

 Pulmonary circulation disease

133

4.38%

886

4.37%

0.983

 Peripheral vascular disease

265

8.72%

1574

7.76%

0.067

 Paralysis

763

25.10%

2671

13.16%

< 0.001

 Other neurological disorders

876

28.82%

4246

20.93%

< 0.001

 Chronic pulmonary disease

798

26.25%

4568

22.51%

< 0.001

 Diabetes without chronic complications

852

28.03%

4664

22.99%

< 0.001

 Diabetes with chronic complications

490

16.12%

2800

13.80%

0.001

 Hypothyroidism

527

17.34%

3237

15.95%

0.053

 Renal failure

959

31.55%

5683

28.01%

< 0.001

 Liver disease

114

3.75%

866

4.27%

0.184

 Peptic ulcer disease with bleeding

8

0.26%

54

0.27%

0.976

 AIDS

10

0.33%

50

0.25%

0.402

 Lymphoma

22

0.72%

212

1.04%

0.098

 Metastatic cancer

91

2.99%

753

3.71%

0.048

 Solid tumor without metastasis

121

3.98%

1016

5.01%

0.014

 Rheumatoid arthritis/collagen vascular

104

3.42%

934

4.60%

0.003

 Coagulopathy

271

8.91%

1916

9.44%

0.351

 Obesity

619

20.36%

3576

17.62%

< 0.001

 Weight loss

476

15.66%

2393

11.79%

< 0.001

 Fluid and electrolyte disorders

1695

55.76%

10,940

53.92%

0.057

 Chronic blood loss anemia

53

1.74%

306

1.51%

0.326

 Deficiency anemia

833

27.40%

4870

24.00%

< 0.001

 Alcohol abuse

46

1.51%

450

2.22%

0.012

 Drug abuse

88

2.89%

655

3.23%

0.329

 Psychosis

139

4.57%

801

3.95%

0.102

 Depression

635

20.89%

3454

17.02%

< 0.001

 Hypertension

2063

67.86%

13,378

65.93%

0.036

Charlson Comoribidity Score

 0

344

11.32%

4046

19.94%

< 0.001

 1

413

13.59%

3534

17.42%

 2

669

22.01%

3893

19.19%

 3

517

17.01%

3052

15.04%

 4

375

12.34%

2069

10.20%

 5+

722

23.75%

3697

18.22%

 Mean (SD)

3.1 (2.3)

2.6 (2.4)

< 0.001

 Median [IQR]

3 [2,4]

2 [1,4]

< 0.001

Hospital Characteristics

 Census region

  Midwest

956

31.45%

6829

33.66%

< 0.001

  Northeast

370

12.17%

2653

13.07%

  South

1406

46.25%

8412

41.46%

  West

308

10.13%

2397

11.81%

Number of Beds

  < 100

121

3.98%

1010

4.98%

 

  100 to 199

373

12.27%

2623

12.93%

0.001

  200 to 299

667

21.94%

4138

20.39%

  300 to 399

524

17.24%

3051

15.04%

  400 to 499

504

16.58%

3567

17.58%

  500+

851

27.99%

5902

29.09%

 Teaching

1258

41.38%

8482

41.80%

0.661

Urban

2623

86.28%

17,599

86.73%

0.815

C3R Rate at Hospital Level

 Mean (SD)

17.0% (7.6%)

14.8% (6.8%)

< 0.001

 Median [IQR]

16.3% [12.4, 20.9%]

14.4% [10.2, 17.7%]

< 0.001

TR Rate at Hospital Level

 Mean (SD)

15.7% (6.4%)

12.6% (5.7%)

< 0.001

 Median [IQR]

15.1% [11.3, 18.8%]

12.2% [9.4, 16.1%]

< 0.001

  1. MDR multidrug resistant, SD standard deviation, SNF skilled nursing facility, ICF intermediate care facility, AIDS acquired immune deficiency syndrome, IQR interquartile range, C3R 3rd generation cephalosporin-resistant, CR carbapenem resistant